Table 1 Clinical and histopathological characteristics of the whole cohort
Number of patients | 335 |
Age at diagnosis | 48.9 ± 12.6 (range 16–81) years |
Gender | 264F (78.8 %) |
71 M (21.2 %) | |
Hyperthyroidism | 46/335 (13.7 %) |
Graves | 21/46 (45.7 %) |
Hashimoto | 47/335 (14 %) |
Family history | 5/335 (1.5 %) |
Singlenodular | 87/335 (26 %) |
Multinodular | 248/335 (74 %) |
Incidental | 274 (81.8 %) |
Non-incidental | 61 (18.2 %) |
Unifocal | 215/335 (64.2 %) |
Multifocal | 120/335 (35.8 %) |
<or = 5 mm | 109/215 (50.7 %) |
>5 mm (of unifocal cases) | 106/215 (49.3 %) |
Metastases | 0/335 (0 %) |
Capsule involvement | 68/335 (20.3 %) |
T > 1 and/or N > 0 | 36/335 (10.7 %) |
Histological types | 170/335 (50.7 %) CPC |
61/335 (18.2 %) EFVC | |
58/335 (17.3 %) N-EFVC | |
41/335 (12.3 %) SVC | |
5/335 (1.5 %) T-CVC | |
Total or near total thyroidectomy | 292/335 (87.2 %) |
I131 | 259/335 (77.3 %) |
Follow up | 10.6 ± 5.3 (median 9, range 5–33) years |
Recurrence | 2/335 (0.6 %) |
Persistence | 13/335 (3.9 %) |
Disease free | 320/335 (95.5 %) |