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Table 1 Host distribution of the predicted hairpin RNA secondary structures in the NS gene positive-sense RNA of influenza A viruses

From: The influenza A virus NS genome segment displays lineage-specific patterns in predicted RNA secondary structure

Influenza A virus (IAV)

Number of strains

Predicted secondary structure %

Nt 82–148

Nt 497–564

Hairpin (%)

Multi-branch stem-loop (%)

Hairpin (%)

Human IAVs

12,192

18

41

52

 Human H1N1 IAVs

1483

88

3

87*

 Human H2N2 IAVs

128

90

1

5*

 Human H3N2 IAVs

5342

8*

4

1*

 Human H1N1pdm2009 IAVs

4913

2*

97*

98*

 Human and swine IAVs of avian origin (e.g., H5, H7, and H9)

279

91

6

69*

Swine IAV

2794

10

58

50

 Swine triple reassortant IAVs

1467

1

69*

14*

 “Classical” swine IAVs lineage

349

4

46*

88*

 “Eurasian” swine IAVs lineage

382

55*

0*

98*

Avian IAVs

9674

60

35

90

Canine IAVs

234

95

0

85

Equine IAVs

153

91

2

8

Environmental IAVs

337

73

13

66

IAVs from other species

94

70

10

79

  1. Nt nucleotide positions
  2. * Differences are statistically significant (p < 0.5)