Fig. 5

Diagnostic performance of the LDT for SFN. a Multiple comparisons graphic, retrieved after one-way analysis of variance (ANOVA) of IENF data obtained using gold standard staining (GS-EFNS) of skin biopsies from healthy volunteers and SFN patients (*** p < 0.001). b Diagnostic performance of LDT for variable Total ENF/mm: area under the ROC curve of 0.72 and p = 0.031 with a sensitivity of 80 % and specificity of 64 %. The lower average Total ENF linear density value in the tested control group, 11.02 Total ENF/mm, was used as cut-off