Table 1 Clinical characteristics and genotypes of patients infected with influenza A(H1N1)pmd09 virus
Characteristics | All patients | Non-hospitalized | Hospitalized | p | |
|---|---|---|---|---|---|
Survived | Died | ||||
N | 436 | 192 | 144 | 100 | |
Female gender | 274 (62.8) | 116 (60.4) | 92 (63.9) | 66 (66.0) | 0.616a |
Age (year) | 24.6 ± 15.6 | 23.6 ± 14.3 | 21.4 ± 15.0 | 30.9 ± 17.1 | <0.001 b |
Pregnant | 63 (32.1) | 23 (28.4) | 18 (28.1) | 22 (43.1) | 0.157a |
Smoking | 23 (5.3) | 7 (3.6) | 6 (4.2) | 10 (10.0) | 0.081a |
Abnormal chest radiograph | 135 (31) | 0 (0) | 70 (48.6) | 65 (65.0) | <0.001 a |
Without comorbidities | 286 (65.6) | 52 (27.1) | 53 (36.8) | 45 (45.0) | 0.007 a |
With comorbidities | |||||
Chronic lung disorder | 86 (19.7) | 33 (17.2) | 36 (25.0) | 17 (17.0) | 0.169a |
Chronic cardiovascular condition | 32 (7.3) | 10 (5.2) | 10 (6.9) | 12 (12.0) | 0.110a |
Metabolic disorder | 19 (4.4) | 2 (1.0) | 6 (4.2) | 11 (11.0) | 0.001 a |
Immunosuppression | 8 (1.8) | 0 (0) | 1 (0.7) | 7 (7.0) | <0.001 a |
Obesity | 9 (2.1) | 1 (0.5) | 1 (0.7) | 7 (7.0) | 0.001a |
Hemoglobinopathy | 3 (0.7) | 1 (0.5) | 1 (0.7) | 1 (1.0) | 0.895a |
Chronic kidney disease | 4 (0.9) | 1 (0.5) | 2 (1.4) | 1 (1.0) | 0.822a |
Genetic ancestry | |||||
Native American | 0.201 (0.029;0.932) | 0.186 (0.022;0.610) | 0.219 (0.041;0.821) | 0.213 (0.035;0.906) | 0.345c |
European | 0.613 (0.046;0.930) | 0.638 (0.046;0.919) | 0.585 (0.095;0.928) | 0.578 (0.059;0.930) | 0.026 c |
African | 0.132 (0.022;0.676) | 0.125 (0.022;0.610) | 0.138 (0.30;0.676) | 0.149 (0.024;0.504) | 0.036 c |
FCGR2A His131Arg (rs1801274) | |||||
AA | 157 (36.0) | 73 (38.0) | 47 (32.6) | 37 (37.0) | |
AG | 195 (44.7) | 80 (41.7) | 74 (51.4) | 41 (41.0) | 0.388a |
GG | 84 (19.3) | 39 (20.3) | 23 (16.0) | 22 (22.0) | |
Ad | 509 (58.4) | 226 (58.9) | 168 (58.3) | 115 (57.5) | 0.952a |
Ge | 363 (41.6) | 158 (41.1) | 120 (41.7) | 85 (42.5) | |