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Table 1 Risk factors for being diagnosed with HSV-2 at baseline

From: Prevalence of Herpes Simplex Virus 2 (HSV-2) infection and associated risk factors in a cohort of HIV negative women in Durban, South Africa

Variable Overall number (% of group) Univariate analysis Multivariate analysis
N = 2236 Odds ratio (95% CI) p value Odds ratio (95% CI) p value
Age*
 <23 660 (29.5) 1   1  
 23–27 484 (21.6) 1.76 (1.39–2.23) 0.001 1.75 (1.37–2.23) 0.001
 28–37 564 (25.2) 3.40 (2.67–4.33) 0.001 3.24 (2.50–4.20) 0.001
 38+ 528 (23.6) 6.72 (5.06–8.92) 0.001 6.08 (4.44–8.32) 0.001
Employed/income
 Yes 1842 (82.4) 1.0   1.0  
 No 394 (17.6) 1.85 (1.43–2.36) 0.001 1.43 (1.10–1.87) 0.008
Religion
 Other 1346 (60.2) 1.0   1.0  
 Christian 890 (39.8) 1.09 (0.91–1.30) 0.334
Education
 ≥High school 1550 (69.3) 1.0    
 <High school 686 (30.7) 1.78 (1.47–2.14) 0.001 1.24 (1.01–1.52) 0.037
Age at first sex act (years)
 >15 2123 (94.9) 1.0    
 <15 113 (5.1) 1.33 (0.88–2.02) 0.175
Sex acts per week**
 <3 1282 (57.3) 1.0    
 3+ 954 (42.7) 0.99 (0.83–1.18) 0.934
Sexual partners
 1 partner 606 (27.1) 1.0    
 2 + partners 1630 (72.9) 1.27 (1.06–1.55) 0.011
STI
 C. trachomatis 244 (10.9) 1.07 (0.81–1.42) 0.624 1.51 (1.11–2.04) 0.007
 N. gonorrhea 71 (3.2) 1.89 (1.07–3.31) 0.027 2.37 (1.31–4.29) 0.004
 Syphilis 56 (2.5) 4.62 (1.97–10.81) 0.001 2.88 (1.20–6.94) 0.018
 T. vaginalis 200 (8.9) 1.51 (1.09–2.09) 0.013 1.50 (1.06–2.12) 0.024
Contraception
 None 185 (8.3) 1.0    
 Othera 228 (10.2) 1.75 (1.09–2.81) 0.021
 Hormonal 1196 (53.49) 0.63 (0.44–0.89) 0.008
 Condoms 627 (28.0) 0.52 (0.36–0.74) 0.001
  1. CI confidence interval
  2. aIncludes tubal ligation, intrauterine devices and traditional methods
  3. * Median (IQR) = 27 (23–37); p value for rank test was < 0.001
  4. ** Median (IQR) = 3 (2–4); p value for rank test was 0.511