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Table 1 Risk factors for being diagnosed with HSV-2 at baseline

From: Prevalence of Herpes Simplex Virus 2 (HSV-2) infection and associated risk factors in a cohort of HIV negative women in Durban, South Africa

Variable

Overall number (% of group)

Univariate analysis

Multivariate analysis

N = 2236

Odds ratio (95% CI)

p value

Odds ratio (95% CI)

p value

Age*

 <23

660 (29.5)

1

 

1

 

 23–27

484 (21.6)

1.76 (1.39–2.23)

0.001

1.75 (1.37–2.23)

0.001

 28–37

564 (25.2)

3.40 (2.67–4.33)

0.001

3.24 (2.50–4.20)

0.001

 38+

528 (23.6)

6.72 (5.06–8.92)

0.001

6.08 (4.44–8.32)

0.001

Employed/income

 Yes

1842 (82.4)

1.0

 

1.0

 

 No

394 (17.6)

1.85 (1.43–2.36)

0.001

1.43 (1.10–1.87)

0.008

Religion

 Other

1346 (60.2)

1.0

 

1.0

 

 Christian

890 (39.8)

1.09 (0.91–1.30)

0.334

Education

 ≥High school

1550 (69.3)

1.0

   

 <High school

686 (30.7)

1.78 (1.47–2.14)

0.001

1.24 (1.01–1.52)

0.037

Age at first sex act (years)

 >15

2123 (94.9)

1.0

   

 <15

113 (5.1)

1.33 (0.88–2.02)

0.175

Sex acts per week**

 <3

1282 (57.3)

1.0

   

 3+

954 (42.7)

0.99 (0.83–1.18)

0.934

Sexual partners

 1 partner

606 (27.1)

1.0

   

 2 + partners

1630 (72.9)

1.27 (1.06–1.55)

0.011

STI

 C. trachomatis

244 (10.9)

1.07 (0.81–1.42)

0.624

1.51 (1.11–2.04)

0.007

 N. gonorrhea

71 (3.2)

1.89 (1.07–3.31)

0.027

2.37 (1.31–4.29)

0.004

 Syphilis

56 (2.5)

4.62 (1.97–10.81)

0.001

2.88 (1.20–6.94)

0.018

 T. vaginalis

200 (8.9)

1.51 (1.09–2.09)

0.013

1.50 (1.06–2.12)

0.024

Contraception

 None

185 (8.3)

1.0

   

 Othera

228 (10.2)

1.75 (1.09–2.81)

0.021

 Hormonal

1196 (53.49)

0.63 (0.44–0.89)

0.008

 Condoms

627 (28.0)

0.52 (0.36–0.74)

0.001

  1. CI confidence interval
  2. aIncludes tubal ligation, intrauterine devices and traditional methods
  3. * Median (IQR) = 27 (23–37); p value for rank test was < 0.001
  4. ** Median (IQR) = 3 (2–4); p value for rank test was 0.511