Fig. 3
From: Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report
Photomicrograph of immunohistochemical staining of granular cell tumor: a strong nuclear and cytoplasm staining of S-100 protein (S-100, original magnification 400×); b granular cell staining of vimentin in cytoplasm (vimentin, original magnification 400×); c strong staining in the cytoplasm of granular cells for CD68 (CD68, original magnification 400×); d nuclear staining of granular cells for p53 (p53, original magnification 400×); e Ki-67 immunostaining in the basal and parabasal cells of epithelium and some isolated granular cells (Ki-67, original magnification 400×); f membranous staining in the overlying epithelium for E-cadherin (E-cadherin, original magnification 200×); g immunostaining collagen IV present only in the endothelium (collagen IV, original magnification 400×); h negative expression of cytokeratin in granular cells (cytokeratin AE1/AE3, original magnification 400×)