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Table 2 Immunohistochemical results

From: Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report

Antibody Results Staining site
S-100 +++ Nuclear and cytoplasm of granular cells
Vimentin +++ Cytoplasm of granular cells
CD68 +++ Cytoplasm of the granular cells
p53 ++ Nuclear staining of the basal and parabasal layer of normal epithelium, granular and pseudoepitheliomatous hyperplasia cells
Ki-67 + Nuclei of basal and parabasal layer and some isolated granular cells
E-cadherin +++ Membranous staining in pseudoepitheliomatous hyperplasia cells
Collagen IV ++ Cytoplasm of endothelium cells
Cytokeratin AE1/AE3 +++ Cytoplasm of pseudoepitheliomatous hyperplasia cells
  1. + weak, ++ moderate, and +++ strong