Table 2 Immunohistochemical results
From: Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report
Antibody | Results | Staining site |
|---|---|---|
S-100 | +++ | Nuclear and cytoplasm of granular cells |
Vimentin | +++ | Cytoplasm of granular cells |
CD68 | +++ | Cytoplasm of the granular cells |
p53 | ++ | Nuclear staining of the basal and parabasal layer of normal epithelium, granular and pseudoepitheliomatous hyperplasia cells |
Ki-67 | + | Nuclei of basal and parabasal layer and some isolated granular cells |
E-cadherin | +++ | Membranous staining in pseudoepitheliomatous hyperplasia cells |
Collagen IV | ++ | Cytoplasm of endothelium cells |
Cytokeratin AE1/AE3 | +++ | Cytoplasm of pseudoepitheliomatous hyperplasia cells |