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Table 2 Prevalence of rifampicin-resistant M. tuberculosis in each variable among the total M. tuberculosis cases using Gene Xpert MTB/RIF assay, DMRH, 2015

From: Rifampicin-resistance pattern of Mycobacterium tuberculosis and associated factors among presumptive tuberculosis patients referred to Debre Markos Referral Hospital, Ethiopia: a cross-sectional study

Variables

Resistance pattern

P value

Resistance

N (%)

Sensitive

N (%)

Age, years

 ≤10

2 (22.2)

7 (77.8)

0.02

 11–17

1(14.3)

6 (83.6)

 

 18–30

3 (6.7)

43 (93.3)

 

 31–40

0

25 (100)

 

 41–50

5 (33.3)

10 (66.7)

 

 51–60

0

9 (100)

 

 61–92

1 (16.7)

5 (83.3)

 

Sex

 Male

8 (11.3)

64 (88.7)

0.77

 Female

4 (8.9)

41 (91.1)

 

Residence

 Urban

5 (17.9)

53 (91.2)

0.76

 Rural

7 (11.9)

52 (88.1)

 

HIV infection

 Positive

5 (17.9)

24 (82.1)

0.17

 Negative

7 (8)

81 (92)

 

Reason for diagnosis

 Presumptive TB

3 (5.9)

49 (94.1)

0.22

 Presumptive DR TB

9 (13.8)

56 (86.2)

 

Treatment history with anti-TB drugs

 Previously treated

7 (17.1)

34 (82.9)

0.11

 Previously untreated

5 (6.7)

71 (93.3)

 

Presumptive DR TB

 New

3 (10.7)

25 (89.3)

0.87

 Relapse

5 (19.2)

21 (80.8)

 

 Failure

2 (14.3)

12 (91.7)

 

 MDR-contact

0

1

 

Site of presumptive TB

 Pulmonary

6 (9.4)

58 (90.6)

0.77

 Extra pulmonary

6 (11.3)

47 (88.7)

 

Specimen type

 Respiratory (sputum)

6 (9.5)

58 (90.6)

0.67

 Non-respiratory

6 (11.3)

47 (88.7)

 

Type of non-respiratory specimen

 Pus

4 (8.5)

43 (91.5)

 

 Peritoneal fluid

0

2

 

 Lymph node aspirate

0

1

 

 Pleural fluid

2

1

 

Total

12 (10.3)

105 (89.7)

 
  1. RIF rifampicin resistant, MTB M. tuberculosis, DR TB drug resistant tuberculosis