Antigen
|
Isotype
|
N
|
Low transmission season
|
High transmission season
|
p*
|
---|
Geometric mean
|
(95% CI)
|
Geometric mean
|
(95% CI)
|
---|
MSP3
|
IgG
|
325
|
2.55
|
(2.12, 3.08)
|
7.29
|
(6.12, 8.67)
|
<.0001
|
|
IgG1
|
325
|
4.35
|
(3.85, 4.92)
|
9.41
|
(8.47, 10.44)
|
<.0001
|
|
IgG2
|
325
|
4.95
|
(4.48, 5.47)
|
4.96
|
(4.53, 5.42)
|
0.065
|
|
IgG3
|
325
|
1.33
|
(1.08, 1.63)
|
2.89
|
(2.42, 3.45)
|
<.0001
|
|
IgG4
|
325
|
3.15
|
(2.88, 3.45)
|
2.95
|
(2.64, 3.29)
|
<.0001
|
MSP2a
|
IgG
|
325
|
14.82
|
(11.92, 18.43)
|
33.21
|
(27.79, 39.67)
|
<.0001
|
|
IgG1
|
325
|
3.60
|
(3.11, 4.16)
|
5.73
|
(4.92, 6.67)
|
0.0012
|
|
IgG2
|
325
|
3.38
|
(3.08, 3.71)
|
3.95
|
(3.46, 4.51)
|
<.0001
|
|
IgG3
|
325
|
12.43
|
(10.22, 15.11)
|
15.04
|
(12.48, 18.13)
|
0.0147
|
|
IgG4
|
325
|
2.52
|
(2.08, 3.05)
|
2.64
|
(2.21, 3.15)
|
0.0539
|
MSP2b
|
IgG
|
325
|
24.50
|
(19.63, 30.57)
|
37.01
|
(31.38, 43.66)
|
0.3356
|
|
IgG1
|
325
|
5.66
|
(4.89, 6.55)
|
13.15
|
(11.58, 14.93)
|
<.0001
|
|
IgG2
|
325
|
4.29
|
(3.94, 4.66)
|
3.62
|
(3.12, 4.21)
|
0.1138
|
|
IgG3
|
325
|
11.90
|
(9.56, 14.81)
|
13.73
|
(11.19, 16.85)
|
0.4537
|
|
IgG4
|
325
|
1.65
|
(1.31, 2.08)
|
1.99
|
(1.64, 2.42)
|
0.3316
|
GLURP-R0
|
IgG
|
325
|
3.65
|
(3.03, 4.41)
|
6.31
|
(5.08, 7.84)
|
<.0001
|
|
IgG1
|
325
|
3.76
|
(3.24, 4.35)
|
3.38
|
(2.87, 3.98)
|
0.2451
|
|
IgG2
|
325
|
1.13
|
(1.01, 1.26)
|
4.45
|
(3.93, 5.04)
|
<.0001
|
|
IgG3
|
325
|
1.46
|
(1.24, 1.71)
|
0.97
|
(0.82, 1.14)
|
<.0001
|
|
IgG4
|
325
|
1.62
|
(1.42, 1.85)
|
0.34
|
(0.30, 0.38)
|
<.0001
|
GLURP-R2
|
IgG
|
325
|
33.45
|
(27.73, 40.36)
|
31.60
|
(26.44, 37.77)
|
0.0372
|
|
IgG1
|
325
|
17.59
|
(14.02, 22.06)
|
41.35
|
(34.08, 50.17)
|
<.0001
|
|
IgG2
|
325
|
7.42
|
(5.84, 9.43)
|
30.11
|
(26.56, 34.14)
|
<.0001
|
|
IgG3
|
325
|
16.77
|
(13.17, 21.36)
|
12.87
|
(10.02, 16.52)
|
0.0001
|
|
IgG4
|
325
|
6.87
|
(6.01, 7.85)
|
5.07
|
(4.40, 5.85)
|
<.0001
|
- * p ≤ 0.05 was considered as statistically significant