Antigen | Isotype | N | Low transmission season | High transmission season | p* | ||
---|---|---|---|---|---|---|---|
Geometric mean | (95% CI) | Geometric mean | (95% CI) | ||||
MSP3 | IgG | 325 | 2.55 | (2.12, 3.08) | 7.29 | (6.12, 8.67) | <.0001 |
IgG1 | 325 | 4.35 | (3.85, 4.92) | 9.41 | (8.47, 10.44) | <.0001 | |
IgG2 | 325 | 4.95 | (4.48, 5.47) | 4.96 | (4.53, 5.42) | 0.065 | |
IgG3 | 325 | 1.33 | (1.08, 1.63) | 2.89 | (2.42, 3.45) | <.0001 | |
IgG4 | 325 | 3.15 | (2.88, 3.45) | 2.95 | (2.64, 3.29) | <.0001 | |
MSP2a | IgG | 325 | 14.82 | (11.92, 18.43) | 33.21 | (27.79, 39.67) | <.0001 |
IgG1 | 325 | 3.60 | (3.11, 4.16) | 5.73 | (4.92, 6.67) | 0.0012 | |
IgG2 | 325 | 3.38 | (3.08, 3.71) | 3.95 | (3.46, 4.51) | <.0001 | |
IgG3 | 325 | 12.43 | (10.22, 15.11) | 15.04 | (12.48, 18.13) | 0.0147 | |
IgG4 | 325 | 2.52 | (2.08, 3.05) | 2.64 | (2.21, 3.15) | 0.0539 | |
MSP2b | IgG | 325 | 24.50 | (19.63, 30.57) | 37.01 | (31.38, 43.66) | 0.3356 |
IgG1 | 325 | 5.66 | (4.89, 6.55) | 13.15 | (11.58, 14.93) | <.0001 | |
IgG2 | 325 | 4.29 | (3.94, 4.66) | 3.62 | (3.12, 4.21) | 0.1138 | |
IgG3 | 325 | 11.90 | (9.56, 14.81) | 13.73 | (11.19, 16.85) | 0.4537 | |
IgG4 | 325 | 1.65 | (1.31, 2.08) | 1.99 | (1.64, 2.42) | 0.3316 | |
GLURP-R0 | IgG | 325 | 3.65 | (3.03, 4.41) | 6.31 | (5.08, 7.84) | <.0001 |
IgG1 | 325 | 3.76 | (3.24, 4.35) | 3.38 | (2.87, 3.98) | 0.2451 | |
IgG2 | 325 | 1.13 | (1.01, 1.26) | 4.45 | (3.93, 5.04) | <.0001 | |
IgG3 | 325 | 1.46 | (1.24, 1.71) | 0.97 | (0.82, 1.14) | <.0001 | |
IgG4 | 325 | 1.62 | (1.42, 1.85) | 0.34 | (0.30, 0.38) | <.0001 | |
GLURP-R2 | IgG | 325 | 33.45 | (27.73, 40.36) | 31.60 | (26.44, 37.77) | 0.0372 |
IgG1 | 325 | 17.59 | (14.02, 22.06) | 41.35 | (34.08, 50.17) | <.0001 | |
IgG2 | 325 | 7.42 | (5.84, 9.43) | 30.11 | (26.56, 34.14) | <.0001 | |
IgG3 | 325 | 16.77 | (13.17, 21.36) | 12.87 | (10.02, 16.52) | 0.0001 | |
IgG4 | 325 | 6.87 | (6.01, 7.85) | 5.07 | (4.40, 5.85) | <.0001 |