Variable | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HRa | (95% CI) | P value | HRa | (95% CI) | P value | |
All patients | ||||||
Overweight | 0.54 | (0.29–0.98) | 0.044 | 0.51 | (0.26–0.99) | 0.047 |
Obese | 0.55 | (0.29–1.02) | 0.059 | 0.54 | (0.26–1.15) | 0.109 |
Age (years) ≥ 50 | ||||||
Overweight | 0.31 | (0.06–1.56) | 0.155 | 0.28 | (0.05–1.52) | 0.140 |
Obese | 0.37 | (0.08–1.81) | 0.221 | 0.26 | (0.05–1.45) | 0.125 |
Age (years) < 50 | ||||||
Overweight | 0.69 | (0.35–1.35) | 0.279 | 0.57 | (0.28–1.17) | 0.128 |
Obese | 0.79 | (0.35–1.78) | 0.569 | 0.60 | (0.22–1.60) | 0.309 |
≥2 metastatic sites | ||||||
Overweight | 0.73 | (0.34–1.58) | 0.432 | 0.67 | (0.28–1.56) | 0.349 |
Obese | 1.28 | (0.54–3.07) | 0.574 | 1.43 | (0.54–3.83) | 0.473 |
1 metastatic site | ||||||
Overweight | 0.37 | (0.14–1.01) | 0.051 | 0.49 | (0.13–1.80) | 0.279 |
Obese | 0.36 | (0.14–0.92) | 0.033 | 0.31 | (0.07–1.25) | 0.099 |
≥ 2nd line | ||||||
Overweight | 0.47 | (0.21–1.05) | 0.065 | 0.37 | (0.15–0.92) | 0.032 |
Obese | 0.49 | (0.21–1.15) | 0.100 | 0.48 | (0.17–1.34) | 0.163 |
1st line | ||||||
Overweight | 0.53 | (0.21–1.35) | 0.183 | 0.97 | (0.36–2.64) | 0.953 |
Obese | 0.48 | (0.18–1.29) | 0.146 | 1.60 | (0.35–7.39) | 0.549 |
Hormone receptors (−) | ||||||
Overweight | 0.68 | (0.25–1.85) | 0.450 | 0.71 | (0.23–2.17) | 0.548 |
Obese | 0.57 | (0.21–1.54) | 0.269 | 1.07 | (0.34–3.39) | 0.910 |
Hormone receptors (+) | ||||||
Overweight | 0.60 | (0.27–1.33) | 0.211 | 0.46 | (0.16–1.28) | 0.135 |
Obese | 0.64 | (0.26–1.57) | 0.335 | 0.37 | (0.10–1.30) | 0.120 |
HER2 (−) | ||||||
Overweight | 0.36 | (0.10–1.24) | 0.104 | 0.42 | (0.11–1.68) | 0.221 |
Obese | 0.52 | (0.16–1.69) | 0.279 | 0.58 | (0.06–5.14) | 0.622 |
HER2 (+) | ||||||
Overweight | 0.66 | (0.30–1.46) | 0.307 | 0.56 | (0.24–1.32) | 0.188 |
Obese | 0.51 | (0.22–1.18) | 0.116 | 0.57 | (0.23–1.44) | 0.235 |