Skip to main content

Table 2 Results of proportional hazard Cox regression models for overall survival among overweight and obese patients in comparison with normal BMI patients

From: The impact of baseline body mass index on clinical outcomes in metastatic breast cancer: a prospective study

Variable

Univariate

Multivariate

HRa

(95% CI)

P value

HRa

(95% CI)

P value

All patients

Overweight

0.54

(0.29–0.98)

0.044

0.51

(0.26–0.99)

0.047

Obese

0.55

(0.29–1.02)

0.059

0.54

(0.26–1.15)

0.109

Age (years) ≥ 50

Overweight

0.31

(0.06–1.56)

0.155

0.28

(0.05–1.52)

0.140

Obese

0.37

(0.08–1.81)

0.221

0.26

(0.05–1.45)

0.125

Age (years) < 50

Overweight

0.69

(0.35–1.35)

0.279

0.57

(0.28–1.17)

0.128

Obese

0.79

(0.35–1.78)

0.569

0.60

(0.22–1.60)

0.309

≥2 metastatic sites

Overweight

0.73

(0.34–1.58)

0.432

0.67

(0.28–1.56)

0.349

Obese

1.28

(0.54–3.07)

0.574

1.43

(0.54–3.83)

0.473

1 metastatic site

Overweight

0.37

(0.14–1.01)

0.051

0.49

(0.13–1.80)

0.279

Obese

0.36

(0.14–0.92)

0.033

0.31

(0.07–1.25)

0.099

≥ 2nd line

Overweight

0.47

(0.21–1.05)

0.065

0.37

(0.15–0.92)

0.032

Obese

0.49

(0.21–1.15)

0.100

0.48

(0.17–1.34)

0.163

1st line

Overweight

0.53

(0.21–1.35)

0.183

0.97

(0.36–2.64)

0.953

Obese

0.48

(0.18–1.29)

0.146

1.60

(0.35–7.39)

0.549

Hormone receptors (−)

Overweight

0.68

(0.25–1.85)

0.450

0.71

(0.23–2.17)

0.548

Obese

0.57

(0.21–1.54)

0.269

1.07

(0.34–3.39)

0.910

Hormone receptors (+)

Overweight

0.60

(0.27–1.33)

0.211

0.46

(0.16–1.28)

0.135

Obese

0.64

(0.26–1.57)

0.335

0.37

(0.10–1.30)

0.120

HER2 (−)

Overweight

0.36

(0.10–1.24)

0.104

0.42

(0.11–1.68)

0.221

Obese

0.52

(0.16–1.69)

0.279

0.58

(0.06–5.14)

0.622

HER2 (+)

Overweight

0.66

(0.30–1.46)

0.307

0.56

(0.24–1.32)

0.188

Obese

0.51

(0.22–1.18)

0.116

0.57

(0.23–1.44)

0.235

  1. aHazard ratios (HR) represent risk of death compared with normal BMI (< 25 kg/m2) patients