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Table 7 AUC for potential markers of eGFR decline by ≥ 25% during follow-up

From: High urinary interleukin-2 in late post-transplant period portends a risk of decline in kidney allograft function: a preliminary study

Predictive variables AUC CI p-level
eGFR decline by 25% after 1 year of follow-up, N = 5
 Proteinuria/Cr 0.817 0.584–1.000 0.028
 IL-2/Cr 0.767 0.519–1.000 0.065
 Proteinuria/Cr + IL-2/Cr 0.858 0.670–1.000 0.013
eGFR decline by 25% after 2 years of follow-up, N = 7
 Proteinuria/Cr 0.779 0.561–0.997 0.028
 Time post-transplant 0.705 0.451–0.958 0.108
 Proteinuria/Cr + Time post-transplant 0.799 0.597–1.000 0.019
  1. Only variables that significantly influenced the eGFR decline in univariate logistic regression are included
  2. AUC, areas under the receiver operating characteristic curve; CI, 95%-confidence interval; eGFR, estimated glomerular filtration rate; IL-2, interleukin 2; Cr, creatinine; N, number of patients with certain decline in eGFR