Variables | Thy2 (NÂ =Â 107) | Thy3 (NÂ =Â 38) | Thy4 (NÂ =Â 13) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | OR | CI | P |  | OR | CI | P |  | OR | CI | P | |
Univariate | ||||||||||||
 Age in years mean (SD) | 39.8 (1.4) | 1.6 | 0.2–10.6 | 0.652 | 34.7 (1.3) | 0.05 | 0.003–0.6 | 0.021 | 41.7 (1.4) | 2.3 | 0.04–150.3 | 0.691 |
 No TN | ||||||||||||
  SN No (%) | 27 (25.2) | 0.8 | 0.4–1.4 | 0.375 | 20 (52.6) | 2.5 | 1.2–5.3 | 0.016 | 7 (53.8) | 2.6 | 0.8–8.5 | 0.101 |
  MNG N (%) | 80 (74.8) | 18 (47.4) | 6 (46.2) | |||||||||
 ER | ||||||||||||
  Yes N (%) | 86 (80.4) | 0.9 | 0.5–1.9 | 0.895 | 23 (60.5) | 0.4 | 0.2–0.8 | 0.012 | 12 (78.4) | 2.8 | 0.5–22.7 | 0.335 |
  NO N (%) | 21 (19.6) | 15 (39.5) | 1 (21.6) | |||||||||
 CLN | ||||||||||||
  Normal N (%) | 85 (79.4) | 2.7 | 1.4–5 | 0.001 | 24 (63.2) | 1.2 | 0.6–2.6 | 0.618 | 9 (69.2) | 1.6 | 0.5–5.5 | 0.461 |
  Enlarged N (%) | 22 (20.6) | 14 (36.8) | 4 (30.8) | |||||||||
 Gender | ||||||||||||
  Male N (%) | 15 (14) | 0.9 | 0.4–1.9 | 0.787 | 0 (0) | NA | 2 (15.4) | 1 | 0.2–4.9 | 0.995 | ||
  Female N (%) | 92 (86) | 38 (100) | 11 (84.6) | |||||||||
 Thyroid gland size | ||||||||||||
  Normal N (%) | 9 (8.4) | 0.8 | 0.3–1.9 | 0.549 | 3 (7.9) | 0.7 | 0.2–2.7 | 0.608 | 1 (7.7) | 0.78 | 0.1–5.9 | 0.730 |
  Enlarged N (%) | 98 (91.6) | 35 (92.1) | 12 (92.3) | |||||||||
 Nodule character | ||||||||||||
  Solid N (%) | 19 (17.8) | 1.2 | 0.3–0.97 | 0.040 | 20 (52.6) | 2.2 | 1–4.8 | 0.039 | 7 (53) | 2.7 | 0.8–9 | 0.114 |
  Cystic | 16 (15) | 1 (26.3) | 1 (7.7) | |||||||||
1.2 | 0.5–2.7 | 0.658 | 0.3 | 0.04–2.6 | 0.288 | 1.1 | 0.1–10 | 0.944 | ||||
  Mixed | 72 (67.3) | 17 (44.7) | 5 (38.5) | |||||||||
 Nodule size | ||||||||||||
  > 1 cm | 2 (1.9) | 0.4 | 0.1–2.1 | 0.285 | 0 (0) | NA | 1 (7.7) | 1.8 | 0.2–16.4 | 0.617 | ||
  < 1 cm | 105 (98.1) | 38 (100) | 12 (92.3) | |||||||||
 Thyroid hormones | ||||||||||||
  TSH mean (sd) | 1.2 (3.3) | 1 | 0.9–1.2 | 0.414 | 7.9 (2.9) | 0.9 | 0.7–1.2 | 0.583 | 1.5 (2.9) | 1 | 0.9–1.2 | 0.688 |
  T3 mean (sd) | 4.6 (1.3) | 1.2 | 0.8–1.8 | 0.347 | 4.5 (1.2) | 1.1 | 0.7–1.7 | 0.626 | 3.9 (1.4) | 0.4 | 0.2–0.99 | 0.046 |
  T4 mean (sd) | 13.2 (1.2) | 1.1 | 0.97–1.2 | 0.159 | 12.9 (1.2) | 1 | 0.9–1.2 | 0.593 | 12.6 (1.1) | 1 | 0.8–1.3 | 0.954 |
  BMI mean (sd) | 31.6 (1.2) | 1.5 | 0.1–40.6 | 0.809 | 31.6 (1.2) | 1.7 | 0.02–163.5 | 0.826 | 31.6 (1.2) | 0.05 | 4.248E−50.1 | 0.401 |
Multivariate | ||||||||||||
 Age in years mean (SD) | 39.8 (1.4) | 1.6 | 0.2–13.2 | 0.674 | 34.7 (1.3) | 0.04 | 0.002–0.96 | 0.047 |  |  |  |  |
 No TN | ||||||||||||
  SN No (%) | 27 (25.2) | 0.7 | 0.3–1.3 | 0.239 | 20 (52.6) | 2.4 | 1.0–5.6 | 0.039 |  |  |  |  |
  MNG N (%) | 80 (74.8) | 18 (47.4) | ||||||||||
 ER | ||||||||||||
  Yes N (%) | 86 (80.4) | 1.0 | 0.5–2.1 | 0.999 | 23 (60.5) | 0.4 | 0.16–0.94 | 0.036 |  |  |  |  |
  NO N (%) | 21 (19.6) | 15 (39.5) | ||||||||||
 CLN | ||||||||||||
  Normal N (%) | 85 (79.4) | 3.2 | 1.6–6.1 | < 0.001 | 24 (63.2) | 0.39 | 1–5.6 | 0.039 |  |  |  |  |
  Enlarged N (%) | 22 (20.6) | 14 (36.8) |