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Table 1 Performance MTBDRplus assay in detecting RIF resistance, INH resistance and MDR-TB against phenotypic DST

From: Performance of MTBDRplus assay in detecting multidrug resistant tuberculosis at hospital level

Drug resistance LJ R LJ S LPA R LPA S Sensitivity, % (95% CI) Specificity, % (95% CI) PPV, % (95% CI) NPV, % (95% CI)
MDR (RIF&INH) 49 23 48 24 97.96 (89.15–99.95) 100 (85.18–100.00) 100 (92.60–100.00) 95.83 (78.88–99.89)
INH 54 18 52 20 96.3 (87.25–99.55) 100 (81.47–100.00) 100 (93.15–100.00) 90 (68.3–98.77)
RIF 49 23 49 23 100 (92.72–100.00) 100 (85.18–100.00) 100 (92.72–100.00) 100 (85.18–100.00)
  1. LJ Lowenstein Jensen DST, LPA line probe assay DST, R resistant, S sensitive, CI confidence interval