Table 1 Performance MTBDRplus assay in detecting RIF resistance, INH resistance and MDR-TB against phenotypic DST
From: Performance of MTBDRplus assay in detecting multidrug resistant tuberculosis at hospital level
Drug resistance | LJ R | LJ S | LPA R | LPA S | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) |
|---|---|---|---|---|---|---|---|---|
MDR (RIF&INH) | 49 | 23 | 48 | 24 | 97.96 (89.15–99.95) | 100 (85.18–100.00) | 100 (92.60–100.00) | 95.83 (78.88–99.89) |
INH | 54 | 18 | 52 | 20 | 96.3 (87.25–99.55) | 100 (81.47–100.00) | 100 (93.15–100.00) | 90 (68.3–98.77) |
RIF | 49 | 23 | 49 | 23 | 100 (92.72–100.00) | 100 (85.18–100.00) | 100 (92.72–100.00) | 100 (85.18–100.00) |