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Table 2 Factors associated with poor treatment outcome in Debre Tabor, May 2008–April 2013; N = 303

From: Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia

Variable Treatment outcome COR (95% CI) P value AOR (95% CI) P value
Poor (%) Successful (%)
Sex
 Male 29 (74.4) 144 (54.6) 2.417 (1.132–5.160) 0.023 2.516 (1.101–4.816)* 0.029
 Female 10 (25.6) 120 (45.4) 1   1  
Age group
 ≤ 14 1 (2.6) 19 (7.2) 1 1 1  
 15–24 7 (18.0) 61 (23.1) 10.0 (1.163–85.998) 0.036 8.247 (0.723–94.052) 0.089
 25–34 6 (15.4) 77 (29.2) 4.586 (1.535–13.704) 0.006 6.395 (1.741–23.492)* 0.005
 35–44 6 (15.4) 41 (15.5) 6.754 (2.182–20.905) 0.001 15.157 (3.495–65.743)* 0.000
 45–54 6 (15.4 25 (9.5) 3.596 (1.140–11.347) 0.029 7.576 (1.791–32.052)* 0.006
 55–64 3 (7.7) 22 (8.3) 2.193 (0.677–7.100) 0.190 4.850 (1.099–21.394)* 0.037
 ≥ 65 10 (25.6) 19 (7.2) 3.86 (0.925–16.109) 0.064 7.291 (1.409–37.735)* 0.018
Residence
 Urban 29 (74.4) 158 (59.8) 1.946 (0.91–4.159) 0.086 3.214 (1.201–8.598)* 0.020
 Rural 10 (25.6) 106 (40.2) 1   1  
Baseline smear result
 Smear positive 13 (33.3) 68 (25.8) 1    
 Smear negative 26 (66.7) 196 (74.2) 1.441 (0.701–2.96) 0.320   
Smear result at 2nd month
 Negative 4 (10.3) 63 (23.9) 1   1  
 Positive 7 (17.9) 3 (1.1) 36.75 (6.792–198.842) 0.000 40.132 (5.004–321.839)* 0.001
 Unknown 28 (71.8) 198 (75.0) 16.50 (4.032–67.530) 0.000 14.495 (2.409–87.236)* 0.004
Type of TB
 Smear positive PTB 13 (33.3) 68 (25.8) 1    
 Smear negative PTB 11 (28.2) 94 (35.6) 0.769 (0.344–1.718) 0.522   
 Extrapulmonary TB 15 (38.5) 102 (38.6) 1.257 (0.55–2.873) 0.588   
HIV status
 Negative 19 (48.7) 160 (60.6) 1    
 Positive 6 (15.4) 35 (13.3) 1.184 (0.419–3.346) 0.751 1.360 (0.208–8.910) 0.748
 Unknown 14 (35.9) 69 (26.1) 1.709 (0.81–3.602) 0.159 2.137 (0.338–11.394) 0.387
Patient category
 New 33 (84.6) 234 (88.6) 0.212 (0.071–0.633) 0.005 0.168 (0.035–0.798)* 0.025
 Retreated 6 (15.4) 9 (3.4) 1   1  
 Transferred in 0 (00.0) 17 (6.4)    
 Unknown 0 (00.0) 4 (1.5)    
Year of treatment
 May 2008–April 2009 11 (28.2) 55 (20.8) 0.846 (0.349–2.052) 0.712 0.707 (0.140–3.578) 0.675
 May 2009–April 2010 13 (33.3) 55 (20.8) 1.433 (0.491–4.186) 0.510 0.616 (0.077–4.951) 0.649
 May 2010–April 2011 6 (15.4) 43 (16.3) 2.160 (0.703–6.632) 0.178 1.228 (0.144–10.500) 0.851
 May 2011–April 2012 5 (12.8) 54 (20.5) 2.850 (0.856–9.489) 0.088 2.453 (0.269–22.385) 0.426
 May 2012–April 2013 4 (10.3) 57 (21.6) 1   1  
  1. *Significant at P < 0.05