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Table 1 Genotype distribution in the study population

From: Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning

Gene dbSNP Genotype Frequency Percentage Cumulative
OPRD1 rs533123 CC 74 3.45 3.45
   CT 695 32.45 35.9
   TT 1373 64.1 100
   Total 2142 100  
  rs678849 CC 480 22.13 22.13
   CT 1009 46.52 68.65
   TT 680 31.35 100
   Total 2169 100  
  rs2236857 AA 676 52.65 52.65
   AG 509 39.64 92.29
   GG 99 7.71 100
   Total 1284 100  
OPRM1 rs1799971 AA 1363 76.44 76.44
   AG 393 22.04 98.48
   GG 27 1.51 99.99
   Total 1783 100  
  rs540825 AA 1234 56.07 56.07
   AT 821 37.3 93.37
   TT 146 6.63 100
   Total 2201 100  
  rs562859 AA 950 43.58 43.58
   AG 962 44.13 87.71
   GG 268 12.29 100
   Total 2180 100  
  rs548646 CC 918 42.68 42.68
   CT 965 44.86 87.54
   TT 268 12.46 100
   Total 2151 100  
  rs1323042 AA 590 27.05 27.05
   AC 1083 49.66 76.71
   CC 508 23.29 100
   Total 2181 100  
  rs618207 CC 956 43.51 43.51
   CT 974 44.33 87.84
   TT 267 12.15 99.99
   Total 2197 100  
  rs639855 GG 1247 56.81 56.81
   GT 806 36.72 93.53
   TT 142 6.47 100
   Total 2195 100  
  rs9479757 AA 20 0.91 0.91
   AG 369 16.8 17.71
   GG 1807 82.29 100
   Total 2196 100  
  rs497976 AA 142 6.49 6.49
   AC 804 36.75 43.24
   CC 1242 56.76 100
   Total 2188 100  
OPRK1 rs7815824 AG 155 7.09 7.09
   GG 2032 92.91 100
   Total 2187 100  
COMT rs2020917 CC 904 50.31 50.31
   CT 744 41.4 91.71
   TT 149 8.29 100
   Total 1797 100  
  rs5993882 GG 110 5.05 5.05
   GT 793 36.43 41.48
   TT 1274 58.52 100
   Total 2177 100  
  rs4646312 CC 344 15.87 15.87
   CT 1032 47.6 63.47
   TT 792 36.53 100
   Total 2168 100  
  rs165722 CC 413 22.65 22.65
   CT 926 50.8 73.45
   TT 484 26.55 100
   Total 1823 100  
  rs4633 CC 129 21.57 21.57
   CT 307 51.34 72.91
   TT 162 27.09 100
   Total 598 100  
  rs4680 AA 623 27.9 27.9
   AG 1110 49.71 77.61
   GG 500 22.39 100
   Total 2233 100  
  1. dbSNP single nucleotide polymorphism database identification, OPRD δ-opioid receptor, OPRM μ-opioid receptor, OPRK κ-opioid receptor, COMT catechol-O-methyltransferase, A Adenine, G Guanine; C Cytosine, T Thymine