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Table 3 Immunohistochemal features of gastrointestinal tumors (GISTs)

From: Clinicopathologic features and prognostic grouping of gastrointestinal stromal tumors (GISTs) in Pakistani patients: an institutional perspective

  S100 ASMA CD34 CD117
P (n = 12) N (n = 28) ND (n = 8) P-value P (n = 19) N (n = 24) ND (n = 5) P-value P (n = 34) N (n = 12) ND (n = 2) P-value P (n = 46) N (n = 2) P-value
Site 7 (58.3) 18 (64.3) 5 (62.5) 0.515 10 (52.6) 17 (70.8) 3 (60.0) 0.469 25 (73.5) 3 (25.0) 2 (100) 0.013* 28 (60.9) 2 (100) 1.000
 Stomach (n = 30) 3 (25.0) 4 (14.3) 3 (37.5) 4 (21.1) 4 (16.7) 2 (40.0) 6 (17.6) 4 (33.3) 0 10 (21.7) 0
 Small intestine (n = 10) 2 (16.7) 6 (21.4) 0 5 (26.3) 3 (12.5) 0 3 (8.8) 5 (41.7) 0 8 (17.4) 0
 Large intestine (n = 8)            
Morphology
 Spindle cell (n = 37) 9 (75) 21 (75.0) 7 (87.5) 1.000 12 (63.2) 20 (83.3) 5 (100) 0.462 25 (73.5) 10 (83.3) 2 (100) 0.137 37 (80.4) 0 0.024*
 Eptheloid (n = 3) 1 (8.3) 2 (7.1) 0 2 (10.5) 1 (4.2) 0 1 (2.9) 2 (16.7) 0 2 (4.3) 1 (50.0)
 Mixed (n = 8) 2 (16.7) 5 (17.9) 1 (12.5) 5 (26.3) 3 (12.5) 0 8 (23.5) 0 0 7 (15.2) 1 (50.0)
Grade
 Low (n = 29) 5 (41.7) 17 (60.7) 7 (87.5) 0.123 11 (57.9) 13 (54.2) 5 (100) 0.220 23 (67.6) 5 (41.7) 1 (50.0) 0.263 29 (63.0) 0 0.152
 High (n = 19) 7 (58.3) 11 (39.3) 1 (12.5) 8 (42.1) 11 (45.8) 0 11 (32.4) 7 (58.3) 1 (50.0) 17 (37.0) 2 (100.0)
Prognostic group
 Very low risk (n = 5) 0 4 (14.3) 1 (12.5) 0.668 1 (5.3) 3 (12.5) 1 (20) 0.681 4 (11.8) 0 1 (50.0) 0.190 5 (10.9) 0 1.000
 Low risk (n = 11) 2 (16.7) 6 (21.4) 3 (37.5) 6 (31.6) 4 (16.7) 1 (20) 10 (29.4) 1 (8.3) 0 11 (23.9) 0
 Moderate risk (n = 5) 1 (8.3) 3 (10.7) 1 (12.5) 2 (10.5) 2 (8.3) 1 (20) 4 (11.8) 1 (8.3) 0 5 (10.9) 0
 High risk (n = 27) 9 (75.0) 15 (53.6) 3 (37.5) 10 (52.6) 15 (62.5) 2 (40) 16 (47.1) 10 (83.3) 1 (50.0) 25 (54.3) 2 (100)
  1. P represents positive, N represents negative, ND represents not done
  2. * Significant at 0.05 level