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Fig. 3 | BMC Research Notes

Fig. 3

From: Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts

Fig. 3

Histomorphological features S462 MPNST xenografts. A HE staining of a highly cellular MPNST xenograft. B Tumor cells stain positive S100 (nuclear and cytoplasmatic. C A high Ki-67 labelling index of 45% was determined by MIB-1 staining. D Staining for CD34 was found to be positive for single cells of the xenograft. E Staining for actin was present only in single cells. F HE staining of a hyper-cellular MPNST xenograft. G Strong nuclear p53 expression and H absence of p16 expression

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