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Table 2 Drug related problems and causes in type 2 diabetes patients with hypertension

From: Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study

Variable category Frequency (%)
Number of DRPs
 One 64 (21.3)
 Two 121 (40.3)
 Three 55 (18.3)
 Four 6 (2.0)
Category of DRP and its causes
 Need for additional drug therapy 145 (29.4)
  Medical condition requires the initiation of drug therapy 4 (2.8)
  Preventive drug therapy required to reduce the risk of developing a new condition 124 (85.5)
  Medical condition requires additional pharmacotherapy to attain synergistic or additive effects 12 (8.3)
  Required preventive drug therapy to reduce the risk of developing a new condition & a medical condition requires additional pharmacotherapy to attain synergistic or additive effects 5 (3.4)
 Ineffective drug 138 (27.9)
  The drug not the most effective for the medical problem 114 (82.6)
  The drug product is not effective for the indication being treated 24 (17.4)
  Dosage too low 78 (15.8)
  The dose is too low to produce the desired response 76 (97.4)
Drug interaction reduces the amount of active drug available 2 (2.6)
 Noncompliance 60 (12.2)
  The patient prefers not to take the medication 6 (10.0)
  The patient forgets to take the medication 27 (45.0)
  The drug product too expensive for the patient 3 (5.0)
  The patient prefers not to take the medication & the patient forgets to take the medication 17 (28.3)
  The patient forgets to take the medication & the drug product too expensive for the patient 5 (8.3)
  The patient prefers not to take the medication, the drug product too expensive for the patient & the patient forgets to take the medication 2 (3.3)
 Unnecessary drug therapy 51 (10.3)
  No valid medical indication for the drug 45 (88.2)
  Multiple drug products are being used for a condition that requires single drug therapy 4 (7.8)
  No valid medical indication for the drug & multiple drug products are being used for a condition that requires single drug therapy 2 (3.9)
 Adverse drug reaction 13 (2.6)
  The drug product causes an undesirable reaction that is not dose-related 7 (53.9)
  The drug product contraindicated due to risk factors 6 (46.2)
 Dosage too high 9 (1.8)
  Dose too high 7 (77.8)
  A drug interaction occurs resulting in a toxic reaction to the drug product 2 (22.2)
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