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Table 2 Univariate and multivariate analysis for non-adherence to anti-TB therapy among TB patients attending TB clinic in health centers at Gondar town, Northwest Ethiopia, 2017 (n = 306)
| Variables | Adherence status | COR (95% CI) | AOR (95% CI) | P-value | |
|---|---|---|---|---|---|
| Adherent | Non adherent | ||||
| Sex | |||||
| Male | 133 | 33 | 0.84 (0.48, 1.45) | ||
| Female | 108 | 32 | 1 | ||
| Age | |||||
| 18–28 | 62 | 13 | 1 | 1 | |
| 29–38 | 48 | 13 | 1.29 (0.55, 3.04) | 3.22 (0.68, 15.17) | 0.139 |
| 39–48 | 70 | 13 | 0.89 (0.38, 2.05) | 0.83 (0.18, 3.88) | 0.808 |
| ≥ 49 | 61 | 26 | 2.03 (0.96, 4.32) | 2.44 (0.53, 9.41) | 0.272 |
| Marital status | |||||
| Single | 113 | 22 | 0.24 (0.09, 0.69)* | 0.11 (0.01, 1.60) | 0.105 |
| Married | 91 | 26 | 0.36 (013, 0.99)* | 0.09 (0.01, 1.30) | 0.077 |
| Divorced | 27 | 9 | 0.42 (0.13, 1.38) | 0.15 (0.01, 3.22) | 0.228 |
| Widowed | 10 | 8 | 1 | 1 | |
| Residence | |||||
| Urban | 205 | 51 | 0.73 (0.36,1.46) | ||
| Rural | 36 | 14 | 1 | ||
| Educational status | |||||
| Unable to read and write | 41 | 18 | 0.59 (0.16, 2.12) | 1.28 (0.21, 7.62) | 0.789 |
| Able to read and write | 45 | 20 | 2.62 (0.96, 7.12) | 1.12 (0.20, 6.37) | 0.899 |
| Grade 1–8 | 44 | 5 | 1.24 (0.40, 3.80) | 0.41 (0.06, 3.01) | 0.381 |
| Grade 9–12 | 65 | 10 | 1.01 (0.35, 2.93) | 2.12 (0.34, 13.11) | 0.420 |
| Diploma | 22 | 5 | 1.10 (0.30, 4.07) | 1.48 (0.19, 11.66) | 0.710 |
| Degree and above | 32 | 7 | 1 | 1 | |
| Income (Ethiopian Birr) | |||||
| ≤ 1000 | 102 | 32 | 1 | 1 | |
| 1001–2000 | 60 | 21 | 1.12 (0.59, 2.12) | 1.65 (0.50, 5.51) | 0.414 |
| 2001–3000 | 43 | 7 | 0.52 (0.21, 1.27) | 0.47 (0.09, 2.38) | 0.365 |
| > 3000 | 36 | 5 | 0.44 (0.16, 1.22) | 0.12 (0.01, 1.30) | 0.081 |
| Distance from TB clinic (single trip) (km) | |||||
| < 3 | 65 | 5 | 1 | 1 | |
| 3–5 | 121 | 24 | 2.58 (0.94, 7.08) | 1.83 (0.38, 8.78) | 0.450 |
| > 5 | 55 | 36 | 8.51 (3.12, 23.18* | 4.30 (0.80, 23.16) | 0.090 |
| Type of transportation to the TB clinic | |||||
| Walking/foot | 72 | 12 | 1 | 1 | |
| Public transport | 169 | 53 | 1.88 (0.95, 3.73) | 1.80 (0.54, 6.01) | 0.338 |
| Traveling time (single trip) (min) | |||||
| ≤ 30 | 131 | 17 | 0.30 (0.16, 0.55)* | 0.48 (0.11, 2.11) | 0.330 |
| > 30 | 110 | 48 | 1 | 1 | |
| Cost of traveling (single trip) (n = 222) (Ethiopian Birr) | |||||
| ≤ 10 Birr | 97 | 17 | 0.40 (0.21, 0.77)* | 1.14 (0.25, 5.24) | 0.866 |
| > 10 Birr | 75 | 33 | 1 | 1 | |
| Patients category | |||||
| New | 190 | 45 | 1 | 1 | |
| Treatment failure | 18 | 7 | 1.64 (0.63, 4.17) | 0.52 (0.05, 5.12) | 0.58 |
| Relapse | 24 | 5 | 0.88 (0.32, 2.43) | 0.94 (0.19, 4.75) | 0.94 |
| Return after default | 9 | 8 | 3.75 (1.37, 10.27)* | 0.88 (0.05, 14.39) | 0.93 |
| Treatment phase | |||||
| Intensive phase | 183 | 35 | 1 | 1 | 0.030 |
| Continuation phase | 58 | 30 | 2.70 (1.53, 4.78)* | 2.27 (1.5, 5.94) | |
| HIV status | |||||
| Seronegative | 153 | 52 | 2.30 (1.19, 4.46)* | 1.97 (0.41, 9.39) | 0.651 |
| Seropositive | 88 | 13 | 1 | 1 | |
| TB status disclosure to the family | |||||
| Yes | 192 | 45 | 1 | 1 | |
| No | 49 | 20 | 1.74 (0.94, 3.22) | 1.47 (0.31, 6.90) | 0.626 |
| Number of comorbidity? | |||||
| > 1 | 89 | 49 | 5.23 (2.81, 9.74) | 6.22 (2.21, 17.48)** | 0.001 |
| No or 1 | 152 | 16 | 1 | 1 | |
| Knowledge | |||||
| Good knowledge | 156 | 20 | 1 | 1 | 0.004 |
| Poor knowledge | 85 | 45 | 4.13 (2.29, 7.44)* | 4.11 (1.57, 10.75)** | |
| Patient-provider relationship | |||||
| Good patient-provider relationship | 183 | 32 | 1 | 1 | 0.004 |
| Poor patient-provider relationship | 58 | 33 | 3.25 (1.84, 5.75)* | 4.60 (1.63, 12.97)** | |
| Alcohol intake | |||||
| Yes | 35 | 23 | 3.22 (1.73, 6.00)* | 5.03 (1.54, 16.40)** | 0.007 |
| No | 206 | 42 | 1 | 1 | |
