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TableĀ 3 Association between the three CD38 cutoff levels and the study variables

From: Evaluation of CD38 expression in Sudanese patients with chronic lymphocytic leukemia

Variables

7% cutoff level

20% cutoff level

30% cutoff level

CD38+

CD38āˆ’

P value

CD38+

CD38āˆ’

P value

CD38+

CD38āˆ’

P-value

Age (%)

ā‰„ā€‰60

46.5

19.2

0.64

28.3

37.4

0.41

25.3

40.4

0.53

<ā€‰60

22.2

12.1

13.1

21.2

11.1

23.2

Sex (%)

Male

51.5

18.2

0.09

31.3

38.4

0.28

27.3

42.4

0.39

Female

17.2

13.1

10.1

20.2

9.1

21.2

Lymphadenopathy (%)

Not found

20.2

8.1

0.49

11.1

17.2

0.68

10.1

18.2

0.37

One site

2.0

2.0

1.0

3.0

0.0

4.0

Two sites

9.1

1.0

5.1

5.1

5.1

5.1

Three sites

1.0

1.0

0.0

2.0

0.0

2.0

More than three sites

36.4

19.2

24.2

31.3

21.2

34.3

Splenomegaly (%)

Present

35.4

17.2

0.76

22.2

30.3

0.86

20.2

32.3

0.65

Absent

33.3

14.1

19.2

28.3

16.2

31.3

Hepatomegaly (%)

Present

18.2

7.1

0.68

13.1

12.1

0.21

11.1

14.1

0.36

Absent

50.5

24.2

28.3

46.5

25.3

49.5

Hemoglobin concentration (g/dl) (%)

Severe

11.1

1.0

0.04*

6.1

6.1

0.67

6.1

6.1

0.57

Moderate

18.2

14.1

11.1

21.2

11.1

21.2

Mild

17.2

11.1

11.1

17.2

8.0

20.2

No anemia

22.2

5.1

13.1

14.1

11.1

16.2

TWBCs countā€‰Ć—ā€‰10 9 (%)

<ā€‰50

26.3

8.1)

0.10

13.1

21.2

0.59

12.1

22.2

0.83

ā‰„ā€‰50

42.4

23.2

28.3

37.4

24.2

41.4

Platelet countā€‰Ć—ā€‰10 9 (%)

<ā€‰150

26.3

13.1

0.94

16.1

23.2

0.97

14.1

25.3

0.71

ā‰„ā€‰150

42.4

18.2

25.3

35.4

22.2

38.4

Modified Rai staging system (%)

High risk group

44.4

20.2

0.54

26.3

37.4

0.10

18.2

46.5

0.99

Intermediate risk group

22.2

8.0

13.1

18.2

17.2

13.1

Low risk group

2.0

3.0

2.0

3.0

1.0

4.0

  1. The CD38 expression at cutoff levels of 7%, 20%, and 30%, were 68.7%, 41.4%, and 36.4% respectively. CD38 (7%) showed the highest positive expression, and a significant association (*) with hemoglobin level