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Table 1 Sensitivity, specificity, positive predictive value, negative predictive value, and kappa index for the detection of HBsAg and anti-HCV on DBS compared to plasma

From: Using dried blood spot for the detection of HBsAg and anti-HCV antibodies in Cameroon

 

HBsAg

Anti-HCV

Value

95% CI

p-value

Value

95% CI

p-value

Se

100

[96.3–100]

1

99

[94.5–99.9]

< 0.01

Sp

99

[94.5–99.9]

< 0.01

98

[92.9–99.7]

< 0.01

PPV

99.0

[94.6–99.9]

< 0.01

98

[93.0–99.7]

< 0.01

NPV

100

[96.3–100]

1

99

[94.5–99.9]

< 0.01

Kappa index

0.99

[0.96–1]

–

0.97

[0.93–1]

–

  1. Se, Sp, PPV, and NPV values for anti-HCV were obtained with adjusted cut-off value of 0.73
  2. Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value