Skip to main content
Fig. 2 | BMC Research Notes

Fig. 2

From: Exposure to Yersinia pestis increases resistance to plague in black rats and modulates transmission in Madagascar

Fig. 2

Effect of origin of rats on the survival rate following inoculation of Y. pestis. In the first experiment, F1 rats from plague-endemic area (Betafo) or from plague-free areas (Miandrivazo) (15 rats each) were inoculated once with 15 cfu (6 rats) or 150 cfu of Y. pestis (6 rats) or with BHI as a control (3 rats). In the second experiment, F1 rats from Toamasina (NEA) and Betafo (16 rats each) were inoculated once with 150 cfu of Y. pestis (13 rats) or with BHI as control (3 rats). Animals were blood sampled post-inoculation at day 0, 5, and 18 (Miandrivazo vs. Betafo) and 0, 5, 13 and 25 (Toamasina vs. Betafo). a The Kaplan–Meier survival curves are represented for each lineage: plague-endemic area (grey) and plague-free areas (black). b Kinetics of IgM and c Kinetics of anti-F1 IgG antibodies after inoculation are presented separately for surviving (surv) and deceased rats (dcd)

Back to article page

BMC Research Notes

ISSN: 1756-0500

Contact us