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Table 1 Demographic and spirometric data from patients included in the study

From: Alpha 1-antitrypsin deficiency in patients with chronic obstructive pulmonary disease patients: is systematic screening necessary?

  All COPD patients n = 551 AAT deficiency n = 40 Pi*ZZ n = 11 p-value
Male: female 283:268 21:19 4:7
Age (mean ± SD) 65.2 ± 14.0 63.2 ± 10.2 60.0 ± 7.3 0.19
Smoking (pack-years) 46.5 ± 41.2 34.7 ± 36.9 4.1 ± 11.2 0.02
FEV1 (% predicted) 50.2 ± 20.6 49.1 ± 20.4 37.7 ± 7.9 0.22
FVC (% predicted) 76.3 ± 22.3 79.4 ± 19.2 78.8 ± 21.4 0.75
FEV1/FVC (%) 50.7 ± 13.6 49.0 ± 13.6 41.9 ± 14.6 0.18
  1. The difference among the three groups was analyzed by ANOVA followed by Turkey’s multiple comparison test
  2. COPD chronic obstructive pulmonary disease, SD standard deviation, FEV1 forced expiratory volume at first second, FVC forced vital capacity