All COPD patients n = 551 | AAT deficiency n = 40 | Pi*ZZ n = 11 | p-value | |
---|---|---|---|---|
Male: female | 283:268 | 21:19 | 4:7 | – |
Age (mean ± SD) | 65.2 ± 14.0 | 63.2 ± 10.2 | 60.0 ± 7.3 | 0.19 |
Smoking (pack-years) | 46.5 ± 41.2 | 34.7 ± 36.9 | 4.1 ± 11.2 | 0.02 |
FEV1 (% predicted) | 50.2 ± 20.6 | 49.1 ± 20.4 | 37.7 ± 7.9 | 0.22 |
FVC (% predicted) | 76.3 ± 22.3 | 79.4 ± 19.2 | 78.8 ± 21.4 | 0.75 |
FEV1/FVC (%) | 50.7 ± 13.6 | 49.0 ± 13.6 | 41.9 ± 14.6 | 0.18 |