Study of biofilm formation and antibiotic resistance pattern of gram-negative Bacilli among the clinical isolates at BPKIHS, Dharan

Table 3 Showing association between antibiotics resistance, ESBL production, MBL production, and biofilm production

Antibiotics	ESBL			MBL			Biofilm
	Resistance (%)		P-value	Resistance (%)		P-value	Resistance (%)		P-value
	Producers (%)	Non-producers (%)	P-value	Producers (%)	Non-producers (%)	P-value	Formers (%)	Non-formers (%)	P-value
Amikacin	22.61	30.43	0.174	84.31	17.49	0.001	34.52	17.95	0.002
Gentamicin	41.67	35.21	0.295	82.35	28.13	0.001	42.64	27.35	0.007
Ofloxacin	69.04	46.52	0.001	96.08	44.11	0.001	57.87	43.59	0.01
Levofloxacin	58.33	42.6	0.013	94.12	37.64	0.001	54.31	34.19	0.001
Cefepime	84.52	43.48	0.001	94.12	46.77	0.001	59.39	46.15	0.023
Ceftazidime	100	47.82	0.001	96.08	55.13	0.001	66.5	53.85	0.026
Imipenem	26.19	35.22	0.132	100	19.77	0.001	39.09	22.22	0.002
Piperacillin	72.62	45.65	0.001	90.19	45.62	0.001	57.87	44.44	0.021
Piperacillin-Tazobactum	35.71	27.39	0.153	66.67	22.43	0.001	32.49	24.79	0.148
Colistin	0	0	*	0	0	*	0	0	*
Polymyxin B	16.67	9.38	0.241	20	7.14	0.079	10.71	10	0.33
Tobramycin	66.67	25	0.067	80	14.28	0.001	35.71	20	0.233
Carbenicillin	66.67	34.38	0.126	80	25	0.001	42.86	30	0.267

PolymyxinB, Tobramycin, and Carbenicillin were applied only for Pseudomonas spp.
* No resistance was observed, P-value could not be calculated

ISSN: 1756-0500