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Table 3 Showing association between antibiotics resistance, ESBL production, MBL production, and biofilm production

From: Study of biofilm formation and antibiotic resistance pattern of gram-negative Bacilli among the clinical isolates at BPKIHS, Dharan

Antibiotics ESBL MBL Biofilm
Resistance (%) P-value Resistance (%) P-value Resistance (%) P-value
Producers (%) Non-producers (%) Producers (%) Non-producers (%) Formers (%) Non-formers (%)
Amikacin 22.61 30.43 0.174 84.31 17.49 0.001 34.52 17.95 0.002
Gentamicin 41.67 35.21 0.295 82.35 28.13 0.001 42.64 27.35 0.007
Ofloxacin 69.04 46.52 0.001 96.08 44.11 0.001 57.87 43.59 0.01
Levofloxacin 58.33 42.6 0.013 94.12 37.64 0.001 54.31 34.19 0.001
Cefepime 84.52 43.48 0.001 94.12 46.77 0.001 59.39 46.15 0.023
Ceftazidime 100 47.82 0.001 96.08 55.13 0.001 66.5 53.85 0.026
Imipenem 26.19 35.22 0.132 100 19.77 0.001 39.09 22.22 0.002
Piperacillin 72.62 45.65 0.001 90.19 45.62 0.001 57.87 44.44 0.021
Piperacillin-Tazobactum 35.71 27.39 0.153 66.67 22.43 0.001 32.49 24.79 0.148
Colistin 0 0 * 0 0 * 0 0 *
Polymyxin B 16.67 9.38 0.241 20 7.14 0.079 10.71 10 0.33
Tobramycin 66.67 25 0.067 80 14.28 0.001 35.71 20 0.233
Carbenicillin 66.67 34.38 0.126 80 25 0.001 42.86 30 0.267
  1. PolymyxinB, Tobramycin, and Carbenicillin were applied only for Pseudomonas spp.
  2. * No resistance was observed, P-value could not be calculated