Fig. 1
From: Thermostability and excision activity of polymorphic forms of hOGG1
Representative time course of hOGG1 activity. One strand of this 20 bp duplex contains 8oxoG at the 10th position from the radiolabeled 5′ end. The substrate was incubated with hOGG1, in this case wild-type, for the time indicated, quenched with hot alkali, and then analyzed by denaturing polyacrylamide gel electrophoresis. The 20-mer band corresponds to non-cleaved DNA, while the 9-mer band corresponds to DNA processed by hOGG1