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Fig. 1 | BMC Research Notes

Fig. 1

From: Synthesis of γ-hydroxy-α-(arylmethyl)carboxylic acids from lactones: pathway to a structural motif derived from lactic acid and amino acid analogs?

Fig. 1

Pathway to γ-hydroxy-α-(aryl/alkylmethyl)carboxylates. a Structural motif of 4-hydroxy-2-(phenylmethyl)butanoic acid (1) (2-benzyl-4-hydroxybutanoic acid) in comparison to phenylalanine and 4-hydroxy-2-((N-methylpyrazol-4-yl)methyl)pentanoic acid (2) in comparison to histidine and lactic acid. b General synthetic pathway starting from α-angelica lactone or y-butyrolactone

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