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Table 3 Summary of indicators of diagnostic accuracy of ultrasound characteristics in the identification of thyroid malignancy

From: Diagnostic accuracy of ultrasound characteristics in the identification of malignant thyroid nodules

Ultrasound characteristic Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) LR+ (95% CI)
Hypoechogenicity 66.7% (48.2–82.0%) 74.8% (68.6–80.3) 27.5% (18.1–38.6%) 94.0% (89.5–97.0%) 2.6 (1.9–3.7)
Microcalcification 36.4% (20.4–54.9%) 96.5% (93.3–98.5%) 60.0% (36.0–80.9%) 91.4% (87.1–94.6%) 10.4 (4.6–23.7)
Internal vascularity 48.5% (30.8–66.5%) 79.1% (73.3–84.2%) 25.0% (15.0–37.4%) 91.5% (86.7–94.9%) 2.3 (1.5–3.6)
At least one positive characteristic 87.9% (71.8–96.6%) 58.7% (52.0–65.1%) 23.4% (20.0–27.1%) 97.1% (93.1–98.8%) 2.1 (1.7–2.6)
At least two positive characteristics 54.5% (36.4–71.9%) 92.2% (87.9–95.3%) 50.0% (36.8–63.2%) 93.4% (90.7–95.4%) 7.0 (4.1–12.0)
All three positive characteristics 9.1% (1.9–24.3%) 99.6% (97.6–99.9%) 75.0% (24.3–96.6%) 88.4% (87.3–89.5%) 20.9 (2.2–195.2)
  1. 95% CI 95% confidence interval, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio