Table 1 (a) Overall diagnostic assay performance, (b) Xpert positivity per collection method, stratified by smear microscopy result of the TB cases
From: Mycobacterium tuberculosis detection from oral swabs with Xpert MTB/RIF ULTRA: a pilot study
Mtb detection n/N | Sensitivity (95% CI) | Specificity (95% CI) | ||||
|---|---|---|---|---|---|---|
TB cases | Controls | |||||
(a) | ||||||
15/33 | 0/26 | 45% (29–62) | 100% (89–100) | |||
Subgroup | Lysis buffer n/N | FTA n/N | PBS n/N | Combined n/N | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|---|---|
(b) | ||||||
SM positive cases | 6/10 | 4/10 | 4/9 | 14/29 | 48% (31–66) | |
SM negative cases | 0/0 | 1/3 | 0/1 | 1/4 | 25% (1.2–76) | |
Controls | 0/7 | 0/10 | 0/9 | 0/26 | 100% (89–100) | |