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Table 2 In vitro anti-Toxoplasma gondii growth inhibitory effect (µg/mL), cytotoxic activity (µg/mL), and selective indexes for S. bicolor red leaf oil-like extract and fractions

From: Anti-Toxoplasma activity of Sorghum bicolor-derived lipophilic fractions

Compound

CC50 (95% CI)

IC50 (95% CI)

SI

S. bicolor n-hexane crude extract

34.41 (31.62–37.45)

3.65 (2.07–6.45)

9.43

Hexane-methanol (10:1) fraction of crude extract

16.92 (14.25–20.10)

2.74 (0.71–10.54)

6.18

Hexane fraction of crude extract

7.23 (3.24–16.14)

3.55 (0.73–17.20)

2.04

  1. 95% CI 95% confidence interval for means of triplicate independent assays, CC50 concentration of oil-like extract that caused 50% reduction in viability of human foreskin fibroblasts, IC50 minimum inhibitory concentration of crude and fractionated oil-like substance that inhibits 50% T. gondii tachyzoite growth, SI selectivity index
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BMC Research Notes

ISSN: 1756-0500

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