Table 1 Demographic and clinical characteristics
From: Echocardiographic assessment of asymptomatic US Air Force members with early HIV infection
Characteristic | All subjects (n = 50) |
|---|---|
Age at HIV diagnosis (years) | 28 (7.14) |
Gender, male | 48 (96) |
Race/ethnicity | |
African American | 30 (60) |
Caucasian | 18 (36) |
Other | 2 (4) |
Body-mass index (kg/m2) | 25.4 (3.66) |
Obese | 4 (8) |
Active smoker | 10 (20) |
Hypertension | 4 (8) |
Diabetes mellitus | – |
Hyperlipidemia | 5 (10) |
Family history of cardiovascular disease | 11 (22) |
hs-CRP (mg/dL) | 1.6 (2) |
NT-proBNP (pg/mL) | 19.6 (39.7) |
Echocardiographic findings | |
Left ventricle | |
LV ejection fraction (%) | 63.4 (6) |
GLS (%) | − 0.31 (2.73) |
LV remodelinga | 13 (26) |
LV diastolic dysfunction | 1 (2) |
Indexed LV mass (g/m2) | 70 (13.9) |
Interventricular septal diameter (mm) | 8.6 (1.8) |
Relative wall thickness | 0.37 (0.07) |
Right ventricle | |
Indexed RV area (cm2/m2) | 11.2 (2.1) |
FAC (%) | 43.4 (7) |
RV dilatationb | 7 (14) |
LV diastolic function | |
Indexed LA volume (cm2/m2) | 20.1 (6.3) |
Septal e′ velocity (cm/s) | 11.4 (2.3) |
Lateral e′ velocity (cm/s) | 15.9 (3.2) |
Average E/e′ | 5.9 (1.5) |
Pulmonary artery systolic pressure (mmHg) | 22.5 (3.7) |
HIV disease characteristics | |
CD4 count (cells/μL) | 551 (225.1) |
HIV viral load (copies/mL)c | 112,585 (217,965) |
AIDS diagnosisd | 2 (4) |
Time from last HIV negative test to first positive HIV test (days) | 530 (265.2) |
Estimated duration of infection prior to clinical evaluation (days) | 304 (129.4) |