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Table 2 Spearman’s correlation analysis between serum δ65Cu levels and clinical parameters within the NAFLD patient cohort

From: Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease

 

Spearman’s ρ

p

n

BMI (kg m−2)

0.03

0.89

24

Steatosis on liver biopsy

− 0.22

0.34

21

Ballooning on liver biopsy

− 0.20

0.37

21

Inflammation on liver biopsy

− 0.09

0.71

21

NAS on liver biopsy

− 0.19

0.42

21

Fibrosis on liver biopsy

− 0.13

0.54

24

Presence of NASH (yes/no)

− 0.19

0.38

24

AST (U l−1)

0.25

0.23

24

ALT (U l−1)

0.03

0.89

24

GGT (U l−1)

− 0.05

0.81

24

Bilirubin (mg dl−1)

− 0.07

0.77

20

Glucose (mg dl−1)

0.24

0.30

20

HOMA-IR

0.26

0.27

20

HbA1c (%)

0.09

0.70

23

Diabetes (yes/no)

0.19

0.39

24

Cholesterol (mg dl−1)

0.22

0.39

17

HDL (mg dl−1)

− 0.10

0.71

17

LDL (mg dl−1)

− 0.06

0.80

19

Triglycerides (mg dl−1)

− 0.16

0.50

20

Ferritin (µg l−1)

0.24

0.33

19

Copper (µg dl−1)

0.10

0.69

18

Transferrin (mg dl−1)

− 0.03

0.91

19

Iron (µg dl−1)

− 0.03

0.92

19

  1. NAFL non-alcoholic fatty liver, NASH: non-alcoholic steatohepatitis, BMI: body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyltransferase, Hb Haemoglobin, HbA1c haemoglobin A1c, LDL low-density lipoprotein, HDL high-density lipoprotein, HOMA-IR Homeostasis Model Assessment Insulin Resistance, NAS NAFLD activity score