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Table 1 Detailed patient characteristics of the 62 HIV-positive patients

From: Is real time PCR preferable to the direct immunofluorescence in the diagnosis of Pneumocystis jirovecii pneumonia in HIV-infected patients?

62 HIV positive patients

66 Bronchoalveolar lavage

Statistical significance

Characteristics

Group 1: IF positive

Group 2: IF negative

 

Subjects

30

36

 

Age years (median, IQR)

41 (34.5–50.5)

41.5 (33.7–48)

ns

Male/female

21/9

23/13

ns

HIV background

 CD4 + counts/ml (median, IQR)

39 (11.5– 65)

104.5 (22.7–190)

s

 Viral load copies/ml (median, IQR)

189,058 (84,818.7–671,206.5)

180,009 (43,062.5–745,879.2)

ns

 cART (%)

3 (10%)

26 (72.2%)

s

Symptoms between hospitalisation and BAL

 Fever

19 (63.3)

22 (61.1)

ns

 Cough

25 (83.3)

32 (88.8)

ns

 Dyspnea

20 (66.6)

15 (41.6)

ns

Laboratory analysis

 LDH (U/l)

588.5 (506.7–854.5)

463.5 (384.2–542.5)

s

Outcome

 In hospital death

1 (3.3)

2 (5.5)

ns

Therapy/prophylaxis

 PCP-Prophylaxis before BAL

2 (6.6)

13 (36.1)

s

 PCP-Therapy after BAL

30 (100)

14 (38.8)

s

PCR Pneumocystis results

 Amount of positive qualitative PCR results

30 (100)

1 (2.7)

s

Positive quantitative PCR copies/ml (median, IQR)

506,068.59 (141,239.7–783,667.2)

298

s

  1. Data presented as median (IQR), n (%)
  2. IF immunofluorescence, PCP pneumocystis pneumonia, BAL bronchoalveolar lavage