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Table 1 Analysis based on Cyclin D1 staining results

From: Immunohistochemical expression of Cyclin D1 among Sudanese patients diagnosed with benign and malignant prostatic lesions

 

Cyclin D1 staining result

Total

P value

Negative staining

Positive staining

Gleason score

 Low-grade

2 (5.1%)

37 (94.9%)

39 (25.5%)

0.000

 High-grade

0 (0.0%)

81 (100%)

81 (52.9%)

 Normal

30 (90.9%)

3 (9.1%)

33 (21.6%)

Family history of PC

 No

32 (22.5%)

110 (77.5%)

142 (92.8%)

0.068

 Yes

0 (0.0%)

11 (100%)

11 (7.2%)

Perineural invasion

 No

32 (35.2%)

59 (64.8%)

91 (59.5%)

0.000

 Yes

0 (0.0%)

62 (100%)

62 (40.5%)

Angiolymphatic invasion

 No

32 (22.7%)

109 (77.3%)

141 (92.2%)

0.053

 Yes

0 (0.0%)

12 (100%)

12 (7.8%)

Diagnosisa

 BPH

30 (90.9%)

3 (9.1%)

33 (21.6%)

0.000

 PC

2 (1.7%)

118 (98.3%)

120 (78.4%)

  1. aBPH Benign prostatic hyperplasia, PC Prostate cancer