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Table 1 Baseline characteristics of the whole cohort

From: Scintigraphy evaluation of hyperthyroidism and its correlation with clinical and biochemical profiles

Baseline characteristics (N = 207) Thyroid ultrasound (N = 160)
 Mean age (years) 42.5 + 14.7    Normal (%) 63.8
 Female (%) 75.8    Enlarged (%) 36.2
Presenting symptoms Thyroid ultrasound texture
 Dysphagia and/or hoarseness (%) 3.4    Heterogenous (%) 73.1
 Neck swelling (%) 6.3    Homogenous (%) 26.9
 Neck tenderness (%) 1.9 Thyroid ultrasound vascularity
 Weight loss (%) 7.7    Normal (%) 54.4
 Tremor (%) 6.8    Hypervascular (%) 43.8
 Palpitation (%) 7.7    Hypovascular (%) 1.8
 Fatigue (%) 4.8 Lymph node features in the thyroid ultrasound
 Anxiety (%) 3.4    No lymph node enlargement (%) 62.5
 Insomnia (%) 1.0    Bilateral lymph node enlargement (%) 35
 Headache (%) 2.4    Unilateral lymph node enlargement (%) 2.5
 Nausea and/or vomiting (%) 1.0    Multiple lymph node enlargement (%) 43.7
 Eye manifestations (%) 13.5    Single lymph node enlargement (%) 17.5
 Heat intolerance (%) 1.9 Thyroid uptake scan (N = 207)
Comorbidities    Heterogenous (%) 37.4
 Upper respiratory tract infection (%) 15.0    Homogenous (%) 55.3
 Hypertension (%) 15.0    Not visualized (%) 7.3
 Hyperlipidemia (%) 11.1    Mean uptake (%) 19.1 + 14.4%
 Type II Diabetes (%) 19.3 Diagnosis based on the thyroid uptake scan result
 Type I diabetes (%) 2.4    Graves’ disease (%) 25.6
 Anemia (%) 8.7    Thyroiditis (%) 15.9
 Dermatitis (%) 15.0    Normal (%) 4.3
 Ischemic heart disease (%) 1.4    Normal scan while taking carbimazole (%) 14
 Stroke (%) 1.4    Autonomous nodule (%) 4.3
 Deep vein thrombosis and/or pulmonary embolism (%) 1.4    Toxic multi-nodular goiter (%) 37.2
Medications    Simple goiter (%) 6.3
 Carbimazole usage prior to the thyroid scan (%) 23.7    Nodular goiter with cold nodule (%) 1.0
 Carbimazole usage after the thyroid scan (%) 10.6    Cold nodule (%) 1.0
 Carbimazole usage during the thyroid scan (%) 25.1    Toxic multi-nodular goiter with a cold nodule (%) 2.4
 Propranolol (%) 29.0    Marine-Lenhart syndrome (%) 1.0
 Levothyroxine (%) 8.7    Recurrnt hyperthyroidism after surgical resection (%) 1.0
 Amiodarone (%) 0.5 Year of the nuclear scan
 Artificial eye tears (%) 5.8    2019 8.2
Laboratory data    2018 22.2
 TSH (milli-international units per liter) 1.2 + 8.5    2017 26.1
 Free T4 (pmol/L) 20.3 + 10.0    2016 43.5
 Free T3 (pmol/L) 9.8 + 8.8 Biochemical diagnosis
 Antithyroid peroxidase antibody (IU/mL) 322.2 + 531.8    Subclinical hyperthyroidism 42.5
 Antithyroglobulin antibody (IU/mL) 336.2 + 901.1    Hyperthyroidism 43.5
 Vitamin D (ng/mL) 22.0 + 9.8    Euthyroidism 8.2
 Erythrocyte sedimentation rate (ESR) (mm/hr) 32.5 + 22.8    T3 thyro-toxicosis 1.4
 C-Reactive protein (CRP) (mg/L) 10.0 + 10.9    Hypothyroidism 1.4
   Subclinical hypothyroidism 1.9
  1. This table shows the baseline characteristics of the whole cohort using the means and standard deviations for quantitative variables like the age, thyroid uptake scan and laboratory parameter. Percentages were used to express all other qualitative data