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Table 1 Top 35 ATAC-seq peaks in blood cells of 1-year old fish derived from cortisol-treated embryos

From: Chronic cortisol exposure in early development leads to neuroendocrine dysregulation in adulthood

Peak Score

Nearest gene

Location

Distance to TSS

198.6

chac1a

Promoter-TSS

− 173

184.4

nlk2

Intergenic

− 1209

184.3

klf9a,b

Promoter-TSS

− 173

180.9

spns2

Intergenic

− 25,446

176.4

mir7a-3

TTS

685

173.1

LOC564840

Promoter-TSS

− 90

172.2

stat3

Promoter-TSS

− 148

171.3

abhd12

Intron (1 of 13)

765

170.7

impdh2

Promoter-TSS

− 218

169.2

gpr146

Promoter-TSS

− 234

168.7

ppp2ca

Promoter-TSS

− 92

167.4

mtmr3

Intron (1 of 19)

14,093

164.4

tmem57b

Promoter-TSS

− 181

163.9

cep57l1

Intergenic

− 3276

163.7

sgk1b

Promoter-TSS

− 128

163.6

rab40b

Promoter-TSS

− 90

158.6

etnk2

Intergenic

− 117,052

156.3

dus1l

Intergenic

− 4036

155.8

txnipa

Promoter-TSS

− 174

155.7

glcci1b

Promoter-TSS

− 153

154.9

zranb1b

Intergenic

− 9055

154.7

mir144

Promoter-TSS

− 502

154.6

znf410

Intergenic

− 15,262

154.3

capgb

Intergenic

− 16,617

150.9

osgn1

Promoter-TSS

− 117

150.1

fkbp5a,b

Promoter-TSS

− 159

149.8

klf11a

Promoter-TSS

− 85

149.8

snrnp48

Intergenic

− 8447

149.4

gsk3b

Promoter-TSS

− 182

148.7

stat2

Intergenic

− 1577

147.9

cct4

Intergenic

29,573

147.3

gc2

Intergenic

44,685

145.7

hprt1l

Promoter-TSS

− 91

145.2

dyrk1b

Intron (1 of 11)

42,251

144.0

hlfa

Intergenic

− 3552

  1. aFound by RNA-seq to be strongly upregulated in cortisol-treated larvae at 5 dpf
  2. bKnown GR target in mammals