Urinary neutrophil gelatinase-associated lipocalin values alone and combined with Prognostic Index predict septic AKI, DIC, and shock: a pilot study

Table 3 Predictive factors for septic AKI, ARDS, Shock, and DIC (univariate analysis)

Variable	AKI (n = 20)	ARDS(n = 5)	Shock (n = 27)	DIC (n = 15)
Variable	P value	P value	P value	P value
Age	0.822	0.335	0.708	0.264
Gender	0.246	0.480	1.000	1.000
Cancer	0.651	0.359	0.526	0.333
Coronary artery disease	0.356	1.000	0.386	1.000
Diabetes mellitus	0.213	0.394	0.634	1.000
Hypertension	0.036	0.586	0.158	1.000
Albumin	0.723	0.810	0.141	0.275
CRP	0.038	0.671	0.588	0.116
WBC	0.120	0.365	0.152	0.328
Neutrophil	0.120	0.385	0.233	0.665
Lymphocytes	0.706	0.839	0.057	0.012
Platelet count	0.540	0.739	0.177	0.000
Fibrinogen	0.448	0.825	0.043	0.072
Survival	0.103	0.116	0.090	0.284
Septic AKI		0.160	0.124	0.059
Septic ARDS	0.099		0.634	1.000
Septic shock	0.090	0.634		0.021
Septic DIC	0.042	1.000	0.021
NGAL: Day 1	0.001	0.189	0.049	0.003
NGAL: Day 2	0.000	0.401	0.120	0.054
NGAL: Day 3	0.004	0.547	0.057	0.139
NGAL: Day 4	0.019	0.773	0.096	0.157
ΔNGAL: Day 2-Day 1	0.736	0.267	0.794	0.332
ΔNGAL: Day 3-Day 1	0.351	0.423	0.417	0.459
ΔNGAL: Day 4-Day 1	0.571	0.962	0.824	0.707
GPS	0.390	0.709	0.935	0.222
NLR	0.300	0.471	0.990	0.480
PLR	0.572	0.753	0.691	0.304
PI	0.084	0.596	0.299	0.885
PNI	0.860	0.725	0.101	0.113
iNS- GPS	0.024	0.158	0.688	0.045
iNS- NLR	0.001	0.756	0.115	0.021
iNS- PLR	0.022	0.472	0.284	0.492
iNS- PI	0.001	0.264	0.308	0.064
iNS- PNI	0.043	0.419	0.840	0.273
SOFA	0.723	0.568	0.020	0.348
qSOFA	0.294	0.493	0.309	0.508

AKI acute kidney injury, ARDS acute respiratory distress syndrome, DIC disseminated intravascular coagulation, CRP C-reactive protein, WBC white blood cell, NGAL neutrophil gelatinase-associated lipocalin, GPS Glasgow Prognostic Score, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, PI prognostic index, PNI prognostic nutritional index, iNS inflammation-NGAL score, qSOFA quick Sequential Organ Failure Assessment

ISSN: 1756-0500