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Table 1 General characteristics of the patients with nephrotic syndrome and the healthy individuals enrolled in the study

From: Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome

Parameter

Control

Non-ATN

ATN

PRO

P value

Total (n)

10

9

10

8

 

Gender

 Female

5 (50%)

4 (44%)

5 (50%)

5 (63%)

Age (years)a

30 [25.5–36.75]

25 [21.5–50.5]

50.5 [20–56]

25.5 [22–46.7]

ns

Serum urea (mg/dl)a

25 [22.75–28.9]

33 [20–47]

64 [37.5–107]

36.5 [24.2–89.5]

ns

Serum creatinine (mg/dl)a

0.9 [0.82–0.97]

1.1 [0.8–1.7]

1.4 [0.7–2.0]

1.7 [0.7–2.0]

ns

Serum albumin (g/dl)a

1.9 [1.6–2.2]

1.7 [1.6–1.8]

2.3 [1.7–2.8]

0.04*

Total cholesterol (mg/dl)a

360.5 [256–470]

372 [278.5–581.8]

235 [139–291]

0.02*

24-h protein (mg)a

6965 [3913–13,437]

7540 [3482–13,844]

8488 [2860–16,081]

ns

SAH

8 (89%)

9 (90%)

5 (63%)

ns

Histological diagnostic

 MCD

4 (44%)

4 (40%)

0

 FSGS

3 (33%)

3 (30%)

  

 MN

2 (22%)

2 (20%)

0

 NL

0

0

4 (50%)

 DPGN

0

0

2 (25%)

 MPGN

0

1 (10%)

2 (25%)

Tubulointerstitial fibrosisb

 

7.7 ± 7.9%

9.4 ± 7.6%

8.1 ± 7%

Acute tubular necrosis (ATN)

0

10 (100%)

7 (88%)

 

Intensity ATNb

3.3 ± 2.5%

46 ± 26.1%

29.3 ± 26.7%

  1. SAH systemic arterial hypertension, MCD minimal change disease, FSGS focal and segmental glomerulosclerosis, MN membranous nephropathy, LN lupus nephritis, DPGN diffuse-proliferative glomerulonephritis, MPGN membranoproliferative glomerulonephritis, ns not significant
  2. * Acute tubular necrosis group (ATN) vs. inflammatory-proliferative glomerular lesion group (PRO)
  3. aData expressed as medians and interquartile intervals
  4. bData expressed as medians ± standard deviations