Fig. 2

Voluntary exercise does not affect asbestos related disease in MexTAg mice. Crocidolite asbestos (6 mg total) was injected into MexTAg mice via two intraperitoneal injections four weeks apart. a Kaplan–Meier plot depicting survival over a 70 week period with the number of mice at risk shown in the corresponding table. b ARD Latency (time from asbestos exposure to first signs of disease) and c progression (time from first signs of disease until cull) in asbestos-exposed groups. Table define experimental design and cohort characteristics. Data are censored for asbestos related deaths and show mean ± SD. Log–rank (Mantel-Cox) analysis was used for survival. Kruskal–Wallis one-way ANOVA with Dunn’s test for multiple comparisons for all other analyses. p values ≤ 0.05 were considered significant. A single age-matched, non-asbestos exposed mouse was culled at week 44 in an incident unrelated to VE