Table 3 List of key reasons for discontinuation
From: What discontinued trials teach us about trial registration?
Reason for discontinuation | % | N |
|---|---|---|
Patient or participant recruitment issues | 37 | 60 |
Related to funding | 17 | 30 |
Substantial changes to procedures or the protocol | 9 | 15 |
Issues related to the purchase or delivery of the trial product | 8 | 13 |
Staff issues, including recruitment, and PI/internal issues | 10 | 16 |
Information indication equipoise resulted in the discontinuation of seven | 4 | 7 |
Objectives were no longer viable | 6 | 9 |
Other reasons (adverse events (5), DSMB decision (2), Regulatory issues (2), and superseded technology (1)) | 6 | 10 |
Unknown | 2 | 4 |