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Table 2 Univariate analysis for association between polymorphisms with and without pelvic organ prolapse

From: Collagen type 1A1, type 3A1, and LOXL1/4 polymorphisms as risk factors of pelvic organ prolapse

Gene SNP ID Allele POP n (%) Control n (%) OR 95% CI P value
COL3A1 rs1800255 GG 21 (40.4) 7 (25.9) 1.0 (ref)   
AG 25 (48.1) 15 (55.6) 0.56 0.18–1.58 0.27
AA 6 (11.5) 5 (18.5) 0.4 0.1–1.76 0.22
COL1A1 rs1800012 CC 52 (100) 28 (100)   
CA 0 0   
AA 0 0   
LOXL1 rs2165241 CC 42 (80.8) 19 (67.9) 1.0 (ref)   
CT 8 (15.4) 8 (28.6) 0.45 0.15–1.40 0.17
TT 2 (3.9) 1 (3.6) 0.9 0.08–20.20 0.94
LOXL4 rs2862296 AA 11 (21.2) 14 (51.9) 1.0 (ref)   
AG 27 (51.9) 9 (33.3) 3.8 1.30–11.80 0.01
GG 14 (26.9) 4 (14.8) 4.5 1.20–19.30 0.02
  1. SNP single nucleotide polymorphisms, ref reference