Table 2 Mean differences of MDADI subscales according to clinical and treatment variables of participants

Time since diagnosis

 New

52.1 ± 17.1

51.9 ± 15.4

44.6 ± 24.3

55.9 ± 16.9

56.5 ± 17.9

47.4 ± 19.0

 6–12 months

52.9 ± 17.4

53.1 ± 16.2

46.7 ± 24.4

54.4 ± 18.9

55.8 ± 17.2

50.7 ± 18.9

 More than year ago

55.3 ± 16.6

55.1 ± 16.3

41.9 ± 20.2

60.1 ± 16.2

61.3 ± 17.4

50.2 ± 20.3

 P

0.729

0.333

0.707

0.389

0.389

0.749

Primary tumor site

 Oral cavity/Oropharyngeal

57.4 ± 20.8

57.4 ± 18.4

52.0 ± 28.1

59.3 ± 20.9

60.7 ± 20.5

54.5 ± 22.8

 Nasal cavity/Nasopharyngeal

55.0 ± 16.4

54.7 ± 16.1

43.9 ± 21.1

59.0 ± 16.4

59.9 ± 16.9

50.8 ± 19.8

 Larynx/ Hypo pharyngeal

47.2 ± 11.5

47.5 ± 11.2

38.1 ± 18.2

50.9 ± 13.8

51.9 ± 14.1

42.7 ± 12.2

 P

0.044*

0.040*

0.058*

0.086

0.084

0.045*

Tumor T stage

 Initial

57.5 ± 18.2

57.7 ± 15.8

50.7 ± 24.9

60.5 ± 18.4

61.8 ± 16.8

53.4 ± 20.8

 Advanced

50.6 ± 15.6

50.3 ± 15.3

40.3 ± 20.8

54.0 ± 16.4

54.9 ± 17.6

46.8 ± 17.9

 P

0.042*

0.019*

0.024*

0.067

0.049*

0.092

Type of carcinoma

 Squamous cell

53.0 ± 16.6

53.3 ± 15.8

44.4 ± 22.1

56.0 ± 17.8

57.2 ± 17.2

49.5 ± 18.8

 Adenocarcinoma

55.6 ± 19.5

54.7 ± 17.4

48.7 ± 25.5

58.3 ± 18.9

60.2 ± 20.2

51.5 ± 22.0

 Other

51.3 ± 15.1

51.2 ± 14.4

38.7 ± 23.3

56.7 ± 13.9

56.0 ± 15.0

45.8 ± 17.2

 P

0.730

0.803

0.425

0.874

0.725

0.676

Treatment modality

 Single modality treatment

50.5 ± 14.7

50.1 ± 14.0

40.9 ± 20.7

55.4 ± 15.9

55.7 ± 16.9

45.2 ± 16.7

 Multi-modality treatment

55.5 ± 18.3

55.8 ± 16.9

47.2 ± 24.5

57.5 ± 18.6

59.2 ± 17.9

52.6 ± 20.6

P

0.148

0.072

0.170

0.555

0.328

0.054