Table 1 Spearman’s correlation between the proportion of each cell type estimated from the methylomic and transcriptomic datasets and Spearman’s correlation between the proportion of each cell type in T0 and T1 for each dataset
From: Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data
Cell type | Comparison between cell counts obtained from methylomic and transcriptomic dataset (n = 20) | Longitudinal correlation in the methylomic dataset (n = 10) | Longitudinal correlation in the transcriptomic dataset (n = 10) | ||||
|---|---|---|---|---|---|---|---|
Coefficient | Significance | Significance after BH correction | Coefficient | Significance | Coefficient | Significance | |
CD8T | 0.45 | 0.044 | 0.044 | 0.79 | 0.007 | 0.79 | 0.006 |
CD4T | 0.81 | < 10−4 | < 10−4 | 0.72 | 0.019 | 0.81 | 0.005 |
NK | 0.67 | 1·10−3 | 2·10−3 | 0.55 | 0.100 | 0.26 | 0.467 |
B cell | 0.63 | 3·10−3 | 0.005 | 0.68 | 0.032 | 0.52 | 0.128 |
Monocytes | 0.55 | 0.012 | 0.016 | 0.82 | 0.004 | 0.79 | 0.006 |
Granulocytes | 0.76 | 0.017 | 0.019 | 0.30 | 0.405 | 0.21 | 0.556 |
Lymphocytes (all) | 0.76 | < 10−4 | 3·10−4 | 0.38 | 0.276 | 0.66 | 0.038 |