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Table 1 Spearman’s correlation between the proportion of each cell type estimated from the methylomic and transcriptomic datasets and Spearman’s correlation between the proportion of each cell type in T0 and T1 for each dataset

From: Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data

Cell typeComparison between cell counts obtained from methylomic and transcriptomic dataset (n = 20)Longitudinal correlation in the methylomic dataset (n = 10)Longitudinal correlation in the transcriptomic dataset (n = 10)
CoefficientSignificanceSignificance after BH correctionCoefficientSignificanceCoefficientSignificance
CD8T0.450.0440.0440.790.0070.790.006
CD4T0.81< 10−4< 10−40.720.0190.810.005
NK0.671·10−32·10−30.550.1000.260.467
B cell0.633·10−30.0050.680.0320.520.128
Monocytes0.550.0120.0160.820.0040.790.006
Granulocytes0.760.0170.0190.300.4050.210.556
Lymphocytes (all)0.76< 10−43·10−40.380.2760.660.038
  1. NK natural killer cells, CD8T CD8 T lymphocytes, CD4T CD4 T lymphocytes, B cell B lymphocytes, BH Benjamini–Hochberg