From: Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data
Cell type | Comparison between cell counts obtained from methylomic and transcriptomic dataset (n = 20) | Longitudinal correlation in the methylomic dataset (n = 10) | Longitudinal correlation in the transcriptomic dataset (n = 10) | ||||
---|---|---|---|---|---|---|---|
Coefficient | Significance | Significance after BH correction | Coefficient | Significance | Coefficient | Significance | |
CD8T | 0.45 | 0.044 | 0.044 | 0.79 | 0.007 | 0.79 | 0.006 |
CD4T | 0.81 | < 10−4 | < 10−4 | 0.72 | 0.019 | 0.81 | 0.005 |
NK | 0.67 | 1·10−3 | 2·10−3 | 0.55 | 0.100 | 0.26 | 0.467 |
B cell | 0.63 | 3·10−3 | 0.005 | 0.68 | 0.032 | 0.52 | 0.128 |
Monocytes | 0.55 | 0.012 | 0.016 | 0.82 | 0.004 | 0.79 | 0.006 |
Granulocytes | 0.76 | 0.017 | 0.019 | 0.30 | 0.405 | 0.21 | 0.556 |
Lymphocytes (all) | 0.76 | < 10−4 | 3·10−4 | 0.38 | 0.276 | 0.66 | 0.038 |