Table 2 Distribution of FCN3 genotypes (rs4494157 and rs10794501) in controls and patients with RF

rs4494157

Genotype distribution

 CC

64 (80)

49 (61.25)

43 (53.75)

 CA

10 (12.5)

20 (25)

23 (28.75)

2.61 (1.12–6.08)^a

3.42 (1.48 -7.91) ^b

0.026^a*

0.005^b*

 AA

6 (7.5)

11 (13.75)

14 (17.5)

3.47 (1.24–9.74) ^b

0.026^b*

 CA/AA

16 (20)

31 (38.75)

37 (46.25)

2.53 (1.24–5.14) ^a

3.44 (1.70–6.95) ^b

0.016 ^{a *}

0.0007 ^{b *}

Allele frequencies

 C

138 (86.25)

118 (73.75)

109 (68.12)

 A

22 (13.75)

42 (26.25)

51 (31.88)

2.23 (1.26–3.95)^a

2.93 (1.68–5.14) ^b

0.008^a*

0.0002^b*

rs10794501

Genotype distribution

 TT

58 (72.5)

51 (63.75)

54 (67.5)

n.s

 TA

17 (21.25)

21 (26.25)

16 (20)

 AA

5 (6.25)

8 (10)

10 (12.5)

 TA/AA

22 (27.5)

29 (36.25)

26 (32.5)

Allele frequencies

 T

133 (83.1)

123 (76.9)

124 (77.5)

n.s

  A

27 (16.9)

37 (23.1)

36 (22.5)