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Fig. 2 | BMC Research Notes

Fig. 2

From: Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function

Fig. 2

Altered expression of Ref(2)P through the TH-Gal4 transgene affects longevity and climbing ability. a Longevity assay of Drosophila melanogaster males displaying altered Ref(2)P expression in the dopaminergic neurons. Longevity is depicted by percent survival. Significance is P < 0.05 using the log-rank test with Bonferroni correction. Error bars represent standard error of the mean. b Locomotor assay of D. melanogaster males displaying altered Ref(2)P expression in the dopaminergic neurons. Climbing ability was determined by a nonlinear curve fit (CI = 95%). Error bars indicate standard error of the mean

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