Table 2 Associations between the PCSK9 rs615563 variant and, FBS, lipid homeostasis variables and liver enzyme levels in patients with diabetes
From: Association between the rs615563 variant of PCSK9 gene and circulating lipids and Type 2 diabetes
Variables | Genotype | p-valuea | ||
|---|---|---|---|---|
GG (n = 58) | GA (n = 22) | AA (n = 10) | ||
Sex (M/F) | 24/34 | 13/9 | 5/5 | 0.35 |
Age (years) | 56.5 ± 13 | 54.36 ± 10.5 | 53.5 ± 13 | 0.57 |
BMI (kg/m2) | 28 ± 5 | 26.82 ± 4.5 | 30.5 ± 7 | 0.32 |
FBS (mg/dL)* | 176 (136.-213.) | 169.5 (134–193) | 158 (128–177.5) | 0.2 |
TC (mg/dL)* | 199.87 ± 41.41 | 194.6 ± 45.54 | 198.95 ± 38.95 | 0.95 |
TG (mg/dL)* | 155 (116–214) | 140 (92–246) | 162 (124.25–193) | 0.46 |
HDL-C (mg/dL)* | 45.8 ± 8.84 | 44.54 ± 11 | 46.3 ± 9.8 | 0.75 |
Non-HDL (mg/dL)* | 153.36 ± 38.93 | 152.72 ± 37.92 | 148.3 ± 43.38 | 0.7 |
LDL-C (mg/dL)* | 117.65 ± 39.40 | 109.59 ± 41.85 | 118.70 ± 52.03 | 0.9 |
ALAT (U/I)* | 15 (10–20) | 15 (10–22.5) | 10 (8–19) | 0.29 |
AST (U/I)* | 29(23–36) | 28.5(24–36.25) | 30 (22.5–33.5) | 0.82 |