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Table 3 Type 2 diabetes case–control and incidence analysis rs615563 (G/A)

From: Association between the rs615563 variant of PCSK9 gene and circulating lipids and Type 2 diabetes

 

Non-Diabetic

Diabetic

OR (%95 CI)a

p-value

Type 2 diabetes case–control analysis (n = 590)

 GG

270 (82.3%)

58 (17.7%)

1.78 (0.79–4.44)

0.16

 GA

183 (89.3%)

22 (10.7%)

Reference

 

 AA

47 (82.5%)

10 (17.5%)

1.48(0.84–2.61)

0.17

Allele frequency

 G

72.3%

77%

  

 A

27.7%

23%

  

Type 2 diabetes incidence analysis (n = 580)

 GG

270 (83.6%)

53 (16.4%)

1.55 (0.85–4.39)

0.16

 GA

183 (90.6%)

19 (9.4%)

Reference

 

 AA

47 (85.5%)

8 (14.5%)

1.72 (0.84–2.61)

0.26

Allele frequency

 G

72.3%

78%

  

 A

27.7%

22%

  
  1. aOR from a logistic regression model adjusted for age, sex and BMI