Chronic and moderate consumption of reduced-alcohol wine confers cardiac benefits in a rat model of pulmonary arterial hypertension

Table 1 The effect of RARW consumption on biometric measurements in rats

	C	MCT	RARW	MCT + RARW
Body mass (g)	311.9 ± 21.6	292.6 ± 4.2	291.0 ± 16.3	283.9 ± 12.6
Whole heart mass (g)	1.59 ± 0.11	1.65 ± 0.08	1.44 ± 0.07	1.47 ± 0.10
RV mass (g)	0.23 ± 0.03	0.39 ± 0.03*	0.23 ± 0.04^†	0.29 ± 0.04
Liver mass (g)	18.18 ± 1.30	17.29 ± 0.51	17.49 ± 0.62	17.13 ± 0.89
Tibia length (cm)	4.80 ± 0.20	4.81 ± 0.07	5.02 ± 0.02	4.64 ± 0.12
LV + septal mass (g)	0.93 ± 0.04	0.86 ± 0.03	0.91 ± 0.03	0.89 ± 0.06
(LV + septal mass)/heart mass (g/g)	0.59 ± 0.02	0.52 ± 0.01*	0.64 ± 0.02	0.61 ± 0.02^†
Heart mass/tibia length (g/cm)	0.33 ± 0.03	0.34 ± 0.02	0.29 ± 0.01	0.32 ± 0.02
RV/(LV + septal mass) (g/g)	0.24 ± 0.03	0.45 ± 0.02*	0.25 ± 0.03	0.32 ± 0.03^†
RV/tibia length (g/cm)	0.047 ± 0.007	0.081 ± 0.006*	0.045 ± 0.007^†	0.063 ± 0.008
Heart mass/body mass (g/g)	0.0052 ± 0.0008	0.0057 ± 0.0003	0.0050 ± 0.0002	0.0052 ± 0.0004
Liver mass/body mass (g/g)	0.061 ± 0.009	0.059 ± 0.002	0.060 ± 0.002	0.060 ± 0.001

Rats consumed wine for 7 days before and 28 days after being injected with PAH-inducing MCT
Values are means ± S.E.M
C Control, MCT monocrotaline, RARW reduced-alcohol red wine, RV right ventricular, LV left ventricular
*p < 0.05 (vs C); ^†p < 0.05 (vs MCT); n ≥ 5 per group

ISSN: 1756-0500