Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients

Table 1 Patient’s baseline characteristics

Characteristic	Early stage	Late stage	P value
Disease stage	15	51 (77.2%)	< 0.0001*
Sex (male/female)	12/3	24/20	0.56
Age (median)	19	21	0.48
CSF parasitosis/mL	0	7 × 10⁴	< 0.000*
Fever	4	52 (92.8%)	0.09
Headache	6	45 (80.2%)	0.09
Hepatomegaly	0	2 (3.5%)	0.75
Splenomegaly	0	6 (10.7%)	0.14
Lymphadenopathy	2	8 (14.2%)	0.70
Gait abnormalities	0	11 (19.6%)	0.24
Tremors	0	9 (16.1%)	0.29
Urinary incontinence	0	7 (12.5%)	0.15

ISSN: 1756-0500