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Table 3 Levothyroxine dosage prescribed in subclinical and overt hypothyroid subgroups as well as autoimmune and nonautoimmune subgroups according to trimester wise and preconception status

From: Levothyroxine dosages during pregnancy among hypothyroid women. An experience from a tertiary care center of Karachi, Pakistan, based on data from Maternal Hypothyroidism on Pregnancy Outcomes Study (MHPO-5)

  Subclinical hypothyroidism
(N = 105)
(µg/day)
Overt hypothyroidism
(N = 50)
(µg/day)
Autoimmune hypothyroidism
(N = 78)
(µg/day)
Nonautoimmune hypothyroidism
(N = 202)
(µg/day)
Preconception dosage* 50.0 (50.0) 100.0 (41.8) 85.7 (66.0) 75.0 (50.0)
1st trimester dosage 64.3 (50.0) 100.0 (41.0) 100.0 (75.0) 100.0 (64.3)
2nd trimester dosage 71.4 (50.0) 100.0 (50.0) 100.0 (87.5) 100.0 (71.4)
3rd trimester dosage 78.5 (71.4) 110.7 (51.7) 103.5 (92.8) 100.0 (85.7)
  1. *Dosage reported as medians (IQR)