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Table 3 Comparison of serum cytokines among patient groups according to disease activity based on DAS28-CRP

From: Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity

Serum cytokines

Low disease activity (n = 35)

Moderate disease activity (n = 23)

High disease activity (n = 22)

p value

IGF-1 (pg/ml)

153.070

(98.480, 311.705)

221.250

(110.138, 470.130)

245.990

(191.280, 401.430)

0.036

IGFBP-3 (pg/ml)

5563.720

(5068.687, 6101.353)

5732.090

(5286.497, 6142.102)

5706.875

(5227.440, 6868.740)

0.587

TNF-α (pg/ml)

5.989

(2.821, 13.163)

7.800

(4.736, 12.814)

10.098

(4.945, 13.580)

0.425

IL-1 (pg/ml)

2.189

(1.844, 2.951)

2.410

(2.016, 3.074)

2.557

(2.167, 3.086)

0.167

IL-6 (pg/ml)

2.547

(1.739, 4.286)

4.447

(3.578, 15.119)

33.513

(6.752, 58.346)

 < 0.001

  1. Numeral data are presented as mean ± one standard deviation, or number of patients with percentages in parentheses as appropriates
  2. DAS28-CRP disease activity score in 28 joints with C-reactive protein, IGF insulin-like growth factor, IGFBP insulin-like factor binding protein, IL interleukin, TNF-α tumor necrosis factor alpha